935659-66-8

Basic information

• Product Name: 3-(3,4-dimethoxyphenyl)-7-(tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one
• Synonyms: 3-(3,4-dimethoxyphenyl)-7-(tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one
• CAS NO: 935659-66-8
• Molecular Weight: 382.413
• Mol File: 935659-66-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(3,4-dimethoxyphenyl)-7-(tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-dimethoxyphenyl)-7-(tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one(935659-66-8)
• EPA Substance Registry System: 3-(3,4-dimethoxyphenyl)-7-(tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one(935659-66-8)

Safety Data

• Hazardous Substances Data: 935659-66-8(Hazardous Substances Data)

Upstream product

• 490-78-8 2,5-Dihydroxyacetophenone 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 
• 3557-22-0 1-(2-hydroxy-5-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethan-1-one 
• 935659-63-5 3-iodo-7-((tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one 
• 111841-07-7 2-hydroxy-4-(tetrahydropyran-2-yloxy)acetophenone 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 110-87-2 3,4-dihydro-2H-pyran 

Downstream Products

• 24160-14-3 cladrin 

Relevant articles and documents

Synthesis, antimycobacterial evaluation and pharmacophore modeling of analogues of the natural product formononetin

Abstract The synthesis and antimycobacterial activity of formononetin analogues is hereby reported. Formononetin and its analogue 11E showed 88% and 95% growth inhibition, respectively, against the H37Rv strain of Mycobacterium tuberculosis. Pharmacophore modeling studies indicated that the presence of a hydroxyl group in formononetin and its analogues, is crucial for maintaining activity.

FLAVONOID PPAR AGONISTS

The present invention relates to PPAR agonists, and their use in therapy including the treatment of disease. In particular, the invention relates to flavonoid compounds which are PPAR-gamma agonists and/or PPAR alpha/gamma dual agonists.