3557-22-0

Basic information

• Product Name: Ethanone, 1-[2-hydroxy-5-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-
• CAS NO: 3557-22-0
• Molecular Formula: C13H16O4
• Molecular Weight: 236.268
• Mol File: 3557-22-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[2-hydroxy-5-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-hydroxy-5-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-(3557-22-0)
• EPA Substance Registry System: Ethanone, 1-[2-hydroxy-5-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-(3557-22-0)

Safety Data

• Hazardous Substances Data: 3557-22-0(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 24057-28-1 pyridinium p-toluenesulfonate 

Downstream Products

• 1125671-09-1 3-(4-chlorophenyl)-7-(tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one 
• 935659-66-8 3-(3,4-dimethoxyphenyl)-7-(tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one 
• 1221290-05-6 4-(7-hydroxy-4-oxo-4H-chromen-3-yl)benzonitrile 
• 15485-81-1 7-hydroxy-3-(4'-chlorophenyl)-4H-1-benzopyran-4-one 
• 24160-14-3 cladrin 
• 13351-10-5 2',4'-dihydroxy-4-methoxychalcone 
• 154407-02-0 (E)-1-(2-hydroxy-4-(tetrahydro-2H-pyran-2-yloxy)phenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 98405-96-0 1-{1-[2-(3-Chloro-benzyloxy)-5-(tetrahydro-pyran-2-yloxy)-phenyl]-vinyl}-1H-imidazole 
• 98405-95-9 1-<1-<2-<(3-chlorobenzyl)oxy-5-hydroxy>phenyl>vinyl>-1H-imidazole 
• 177344-55-7 4,2',5'-trihydroxychalcone 
• 98405-94-8 1-<1-<2-hydroxy-5-<(tetrahydropyran-2-yl)oxy>phenyl>vinyl>-1H-imidazole 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis

A series of 4H-chromen-4-one derivatives obtained by scaffold morphing of the benzofuran compound, TAM16, were tested for antitubercular activity. Compound 8d was active against drug-sensitive and multidrug-resistant tuberculosis. A preliminary druggability evaluation showed that compound 8d displayed favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability. An in vivo study indicated that compound 8d exhibited modest efficacy in an acute mouse model of TB after 3 weeks of treatment. Thus, 8d is a promising antituberculosis lead compound.

ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in c

Flavonol based ruthenium acetylides as fluorescent chemosensors for lead ions

Flavonol based alkynyl ruthenium complexes devoted to the detection of metal traces in solution are described. The sensitivity of both absorption and emission properties of the 3-hydroxyflavone unit as a receptor for the metal cations, and of an alkynyl ruthenium moiety as an extended π-conjugated system, provides an efficient molecular sensor for rapid, sensitive and selective detection of lead(II) cations.