936954-12-0

Basic information

• Product Name: N⁴-(4-chloro-2,5-dimethoxyphenyl)-7-ethoxyquinazoline-4,6-diamine
• Synonyms: N⁴-(4-chloro-2,5-dimethoxyphenyl)-7-ethoxyquinazoline-4,6-diamine
• CAS NO: 936954-12-0
• Molecular Weight: 374.827
• Mol File: 936954-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N⁴-(4-chloro-2,5-dimethoxyphenyl)-7-ethoxyquinazoline-4,6-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁴-(4-chloro-2,5-dimethoxyphenyl)-7-ethoxyquinazoline-4,6-diamine(936954-12-0)
• EPA Substance Registry System: N⁴-(4-chloro-2,5-dimethoxyphenyl)-7-ethoxyquinazoline-4,6-diamine(936954-12-0)

Safety Data

• Hazardous Substances Data: 936954-12-0(Hazardous Substances Data)

Upstream product

• 6358-64-1 4-chloro-2,5-dimethoxy-aniline 
• 936954-10-8 4-chloro-7-ethoxy-6-nitroquinazoline 
• 936954-09-5 7-ethoxy-6-nitroquinazolin-4-ol 
• 162012-69-3 7-fluoro-6-nitro-4-hydroxyquinazoline 
• 936954-11-9 N-(4-chloro-2,5-dimethoxyphenyl)-7-ethoxy-6-nitroquinazolin-4-amine 

Downstream Products

• 870962-68-8 (2E)-N-{4-[(4-chloro-2,5-dimethoxyphenyl)amino]-7-ethoxyquinazolin-6-yl}-4-(dimethylamino)but-2-enamide 
• 870962-70-2 C₂₂H₂₂ClN₅O₄ 

Relevant articles and documents

Dual irreversible kinase inhibitors: Quinazoline-based inhibitors incorporating two independent reactive centers with each targeting different cysteine residues in the kinase domains of EGFR and VEGFR-2

A series of 4-dimethylamino-but-2-enoic acid [4-(3,6-dioxo-cyclohexa-1,4-dienylamino)-7-ethoxy-quinazolin-6-yl]-amide derivatives were prepared. These compounds have two independent reactive centers and were designed to function as dual irreversible inhib