937-19-9 Usage
Description
1H-Pyrrole-2-carboxylicacid,5-cyano-,methylester(9CI) is a methyl ester derivative of 1H-pyrrole-2-carboxylic acid with a cyano group at the 5-position. It is a compound with the molecular formula C8H6N2O2 and is commonly used in organic synthesis and pharmaceutical research as a building block for various bioactive molecules and pharmaceutical drugs.
Uses
Used in Organic Synthesis:
1H-Pyrrole-2-carboxylicacid,5-cyano-,methylester(9CI) is used as a building block in organic synthesis for the creation of various bioactive molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, 1H-Pyrrole-2-carboxylicacid,5-cyano-,methylester(9CI) is utilized as a building block for the development of pharmaceutical drugs.
Used in Antimicrobial Applications:
1H-Pyrrole-2-carboxylicacid,5-cyano-,methylester(9CI) has been investigated for its potential antimicrobial properties, making it a candidate for use in applications targeting the inhibition of microbial growth.
Used in Anticancer Applications:
1H-Pyrrole-2-carboxylicacid,5-cyano-,methylester(9CI) has also been explored for its potential anticancer properties, indicating its possible use in cancer research and treatment.
The lipophilic nature of the methyl ester group in 1H-Pyrrole-2-carboxylicacid,5-cyano-,methylester(9CI) may influence its bioavailability and pharmacokinetics, which could be relevant in the development of drugs and other applications within the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 937-19-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,3 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 937-19:
(5*9)+(4*3)+(3*7)+(2*1)+(1*9)=89
89 % 10 = 9
So 937-19-9 is a valid CAS Registry Number.
937-19-9Relevant articles and documents
Synthesis of rhazinilam through intramolecular arylcyanation of alkenes catalyzed cooperatively by nickel/aluminum
Yamada, Yuuya,Ebata, Shiro,Hiyama, Tamejiro,Nakao, Yoshiaki
, p. 4413 - 4417 (2015)
Intramolecular arylcyanation across a tri-substituted double bond proceeds to give a primary alkyl cyanide product through functionalization of C-CN and allylic C-H bonds and double C-C bond formation in a 1,3-manner by cooperative nickel/AlMe2
Dissecting the complex recognition interfaces of potent tetrazole- and pyrrole-based anion binders
Pinter, Thomas,Simhadri, Chakravarthi,Hof, Fraser
, p. 4642 - 4648 (2013/07/05)
Tetrazoles are potent anion binders. We report here a new family of tetrazole-pyrrole-amide hosts that arise when a tetrazole is incorporated as a new binding element alongside the well-known amidopyrrole anion-binding scaffold. In addition to reporting three new, modular synthetic routes that can be used to access these structures, we also report that the new hosts are highly potent binders of chloride. Along the way, we carried out studies of a pyrrole ester control compound that, surprisingly, bound anions almost as strongly as did the amide analogues. This led us to investigate further the relative importance of the amide NH in halide binding. We report that, despite the regular appearance of this close amide NH - -Cl contact in calculated and experimental X-ray structures, the amide NH in this family of anion hosts does not hydrogen bond strongly to chloride in solution.
Photolysis of 2,6-dicyanopyridine 1-oxides.
Ishikawa,Kaneko,Yokoe,Yamada
, p. 295 - 300 (2007/10/07)
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