937254-80-3Relevant articles and documents
SPIROPIPERIDINE DERIVATIVES
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Page/Page column 171, (2010/11/27)
The invention provides compounds of formula (I): wherein the dotted line represents an optional covalent bond between X and Y, and X, Y, Z, m, R2, R3, R4, R5, R6, R7, R8, R9, a and b have the meanings given in the specification, and pharmaceutically acceptable salts and solvates thereof. The compounds are delta opioid receptor agonists and have a number of therapeutic applications, particularly in the treatment of pain.