939981-37-0

Basic information

• Product Name: 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)Ethanone
• Synonyms: 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)Ethanone;Ethanone, 2-[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)-, rel-;p53 and MDM2 proteins-interaction-inhibitor (chiral);Ethanone, 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-diMethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-diMethyl-1H-iMidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-Morpholinyl)-;p53 inhibitor (chiral);2-[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)-ethanone;2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(
• CAS NO: 939981-37-0
• Molecular Formula: C40H49Cl2N5O4
• Molecular Weight: 734.764
• Mol File: 939981-37-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 788.563 °C at 760 mmHg
• Flash Point: 430.708 °C
• Appearance: /
• Density: 1.24
• CAS DataBase Reference: 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)Ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)Ethanone(939981-37-0)
• EPA Substance Registry System: 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)Ethanone(939981-37-0)

Safety Data

• Hazardous Substances Data: 939981-37-0(Hazardous Substances Data)

Usage

General Description

The chemical 2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone is a complex compound with a long and detailed structure. It contains multiple functional groups including piperazine, morpholine, and carbonyl, as well as a variety of substituted phenyl and methyl groups. This chemical may have potential pharmacological activity, and its specific properties and potential uses would likely require further research and investigation.

Upstream product

• 870007-39-9 4-(tert-butyl)-2-ethoxy-benzoic acid methyl ester 
• 1313703-90-0 (4S*,5R*)-4,5-bis(4-chlorophenyl)-2-(4-(tert-butyl)-2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole 
• 939983-16-1 meso-2,3-bis-(4-chlorophenyl)-2,3-butanediamine 
• 39890-46-5 1-morpholino-2-(piperazin-1-yl)ethanone 
• 939981-37-0 (4S,5R)-4-[[4-[[4,5-bis(4-chlorophenyl)-2-[4-(tert-butyl)-2-ethoxy-phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]acetyl]-morpholine 

Relevant articles and documents

Discovery of RG7112: A small-molecule MDM2 inhibitor in clinical development

The p53 tumor suppressor is a potent transcription factor that plays a key role in the regulation of cellular responses to stress. It is controlled by its negative regulator MDM2, which binds directly to p53 and inhibits its transcriptional activity. MDM2