945488-75-5Relevant articles and documents
4-(Isoindolin-5-yl)amino-4-oxobutyryl-β-alkoxyphenyl-β-alanines, new RGDF mimetics. Synthesis, affinity to fibrinogen receptors, antiaggregatory properties, and their correlation with the hydrophobicity
Andronati,Krys'ko,Chugunov,Kabanova,Artemenko
, p. 1174 - 1182 (2007/10/03)
A new series of RGDF mimetics, derivatives of 4-(isoindolin-5-yl)amino-4- oxobutanoic acid, was synthesized. The compounds obtained inhibit efficiently the thrombocytes aggregation in experiments in vitro; their biological targets are fibrinogen receptors