946506-01-0Relevant articles and documents
The synthesis and evaluation of trimeric X-ray contrast agents
Newington, Ian M.,Humphries, Gareth,Lasbistes, Nicolas,Morisson-Iveson, Véronique,Nairne, James,Passmore, Joanna,Thanning, Mikkel,Wistrand, Lars-G?ran,Wynn, Duncan
, p. 3065 - 3067 (2011/06/23)
Novel trimeric iodinated contrast agents with low osmolality have been prepared and evaluated with the aim of improving the already good safety profile of such agents. While the aim of low osmolality was achieved, the viscosity of the trimeric agents was found to be generally higher than current dimeric agents in clinical use.
CONTRAST AGENTS
-
Page/Page column 9, (2008/12/04)
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing an aliphatic N-heterocyclic central moiety such as pyrrolidine or piperidine heterocycles allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging, in particular in X-ray imaging, and to contrast media containing such compounds.
CONTRAST AGENTS
-
Page/Page column 17-18, (2008/06/13)
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing an aliphatic central moiety containing amide functions allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.