94930-83-3Relevant articles and documents
Total Syntheses and Anti-inflammatory Activities of Syringin and Its Natural Analogues
Dong, Hongbo,Du, Weihong,He, Yujiao,Shi, Zheng,Wang, Yingying,Wu, Min
, p. 2866 - 2874 (2021/11/12)
Syringin (1), a natural bioactive glucoside isolated from the root of Acanthopanax senticosus (Rupr. Maxim.) Harms, possesses significant anti-inflammatory activity. In this study, we have accomplished the total syntheses of syringin (1), along with its natural analogues 2-12, from a common starting material, syringaldehyde (13), in 4-8 steps with an overall yields of 11.8-61.3%. The anti-inflammatory activities of these compounds were determined against NO production in the LPS-stimulated RAW264.7 cells. Among them, compounds 1-5, 7, and 9 exhibited different levels of anti-inflammatory activity.
PREPARATION AND REACTIVITY OF 2,6-DIMETHOXY-4-ALLYLIDENE-2,5-CYCLOHEXADIEN-1-ONE (VINYL QUINONE METHIDE) A NOVEL SYNTHESIS OF SINAPYL ALCOHOL
Zanarotti, A.
, p. 3815 - 3818 (2007/10/02)
Title compound (3b), prepared in concentrated CHCl3 or benzene solution and spectroscopically characterized, is shown to be an useful intermediate for the synthesis of sinapyl alcohol (1b) and its derivatives.