41628-47-1

Basic information

• Product Name: 2-Propenoic acid, 3-(4-hydroxy-3,5-dimethoxyphenyl)-, ethyl ester, (2E)-
• CAS NO: 41628-47-1
• Molecular Formula: C13H16O5
• Molecular Weight: 252.267
• Mol File: 41628-47-1.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(4-hydroxy-3,5-dimethoxyphenyl)-, ethyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(4-hydroxy-3,5-dimethoxyphenyl)-, ethyl ester, (2E)-(41628-47-1)
• EPA Substance Registry System: 2-Propenoic acid, 3-(4-hydroxy-3,5-dimethoxyphenyl)-, ethyl ester, (2E)-(41628-47-1)

Safety Data

• Hazardous Substances Data: 41628-47-1(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 134-96-3 syringic aldehyde 
• 53669-33-3 4-acetoxy-3,5-dimethoxybenzaldehyde 
• 106852-80-6 4-(t-butyldimethylsilyloxy)-3,5-dimethoxybenzaldehyde 
• 64-17-5 ethanol 
• 530-59-6 sinapinic acid 
• 530-59-6 trans-3,5-dimethoxy-4-hydroxycinnamic acid 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 1071-46-1 hydrogen ethyl malonate 

Downstream Products

• 110233-74-4 ethyl-(4'-acetoxy-3',5'-dimethoxyphenyl)-prop-2-enoate 
• 56136-42-6 2,3-Bis-[1-(4-hydroxy-3,5-dimethoxy-phenyl)-meth-(Z)-ylidene]-succinic acid diethyl ester 
• 887914-26-3 (1R,2S)-1-(4-hydroxy-3-methoxyphenyl)-2-(4-((E)-3-hydroxyprop-1-en-1-yl)-2,6-dimethoxyphenoxy)propane-1,3-diol 
• 94930-83-3 4-((E)-3-Ethoxy-propenyl)-2,6-dimethoxy-phenol 
• 94930-82-2 2,6-Dimethoxy-4-(3-methoxy-trans-propenyl)-phenol 

Relevant articles and documents

Dietary phenolic acids and derivatives. Evaluation of the antioxidant activity of sinapic acid and its alkyl esters

The action of sinapic acid and its alkyl esters as potential antioxidants has been investigated. For this purpose, a series of sinapic acid ester derivatives was synthesized and their antioxidant activities were evaluated using distinctive analytical meth

Total Syntheses and Anti-inflammatory Activities of Syringin and Its Natural Analogues

Syringin (1), a natural bioactive glucoside isolated from the root of Acanthopanax senticosus (Rupr. Maxim.) Harms, possesses significant anti-inflammatory activity. In this study, we have accomplished the total syntheses of syringin (1), along with its natural analogues 2-12, from a common starting material, syringaldehyde (13), in 4-8 steps with an overall yields of 11.8-61.3%. The anti-inflammatory activities of these compounds were determined against NO production in the LPS-stimulated RAW264.7 cells. Among them, compounds 1-5, 7, and 9 exhibited different levels of anti-inflammatory activity.

Investigating isomer specific photoprotection in a model plant sunscreen

Sinapate esters are used throughout the plant kingdom, for example in photoprotection from ultraviolet radiation. Sinapate esters are naturally produced in their E-isomeric form; however, upon exposure to ultraviolet radiation, photoisomerization drives Z-isomer formation. To elucidate the photoprotection capacity of E vs. Z forms of sinapate esters, we explore the photochemistry of the model system, Z-ethyl sinapate. Following a novel Z-ethyl sinapate synthesis, we demonstrate that photoprotection is isomer independent. This suggests that, regarding photoprotection, there were no evolutionary pressures for biosynthesis of either isomer.