951-00-8Relevant articles and documents
Acridine-based dyes as high-performance near-infrared Raman reporter molecules for cell imaging
Cao, Hui,Du, Jiasheng,He, Wanli,Li, Jinming,Li, Yuzhan,Wang, Dong,Zhou, Yang
, p. 3380 - 3385 (2022/02/09)
A surface-enhanced Raman scattering (SERS) nanoprobe has been proven to be a promising tool for near-infrared (NIR) biomedical imaging and diagnosis because of its high sensitivity and selectivity. However, the development of NIR SERS reporters has been a bottleneck impeding the preparation of ultrasensitive SERS probes. Herein, we report the design and synthesis of a series of SERS reporters in the NIR region based on 10-methylacridine (AD). The AD nanotags (gold nanostar-AD molecules-BSA, AuNS-AD-BSA) exhibit appreciable SERS signals and can be detected at as low as the sub-picomole level. The results of in vitro imaging experiments show that it can be used in live-cell delineation.
Synthesis and spectroscopic and DNA-binding properties of fluorogenic acridine-containing cyanine dyes
Mahmood, Tariq,Paul, Alexis,Ladame, Sylvain
scheme or table, p. 204 - 207 (2010/04/24)
(Chemical Equation Presented) The synthesis of a new subclass of mono- and polymethine cyanine dyes that incorporate an acridinium moiety and that absorb in the orange to near-infrared region of the spectrum is reported. The mono-, tri-, and pentamethine dyes in particular exhibit promising fluorogenic properties. Their ability to aggregate in solution and to interact with B-DNA is also discussed.