95388-08-2Relevant articles and documents
Synthesis method of 1,4-bis(p-toluenesulfonyl)trinitrocyclononane
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Paragraph 0015-0022, (2021/08/21)
The invention discloses a synthesis method of 1,4-bis(p-toluenesulfonyl)trinitrocyclononane. The synthesis method comprises the following steps: with 1,4-bis(p-toluenesulfonyl)-7-benzoyltrinitrocyclononane as a substrate, removing a protecting group of a benzoyl group under an alkaline condition, and conducting a reaction under the condition that two p-toluenesulfonyl groups do not participate in the reaction so as to obtain the 1,4-bis(p-toluenesulfonyl)trinitrocyclononane. Reaction conditions are that a reflux reaction is adopted and reaction time is 10-36 hours. Compared with the prior art, the synthesis method of the invention has the following beneficial effects: the use of a large amount of inorganic acid and organic acid is avoided, and the problems of safety, environmental protection and the like are effectively guaranteed essentially; and reaction yield can be up to 90% or above.
1,2-BIS-(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND INTERMEDIATE THEREOF
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, (2012/02/01)
The present invention provides improved processes for the synthesis of 1,4-ditosyl- 1,4,7-triazacyclonone and protected analogues thereof, and to synthesise bis(triazacyclononane) ligands.
Tripodal tris-tacn and tris-dpa platforms for assembling phosphate-templated trimetallic centers
Cao, Rui,Mueller, Peter,Lippard, Stephen J.
supporting information; experimental part, p. 17366 - 17369 (2011/02/23)
Multidentate tripodal ligands, N(CH2-m-C6H 4-CH2tacn)3 (L1) and N(CH2-o-C 6H4-CH2N(CH2py)2) 3 (L2), have been devised for assembling high-nuclearity metal clusters. By using the same tripodal platform with different ligand appendages, either triazacyclononanes or dipicolylamines, and functionalizing either the ortho or the meta positions on the tris(xylyl) linker arms, discrete trimetal phosphate units of relevance to phosphate-metabolizing trimetallic centers in biology were prepared. Four such compounds, [(CuIICl) 3(HPO4)L1](PF6) (1), [(CuIICl) 3(HAsO4)L1](PF6) (2), Na2[Mn III6MnII2(H2O) 2(HPO4)6(PO4)4(L1) 2] (3), and [CoII3(H2PO 4)Cl2(MeCN)L2](PF6)3 (4), all containing three metal centers bound to a central phosphate or arsenate unit bridging oxygen atoms, have been synthesized and structurally characterized. These results demonstrate the propensity of this novel tripodal ligand platform, in the presence of phosphate or arsenate, to assemble {M3(EO 4)} units and thus structurally mimic trimetallic active sites of proteins involved in phosphate metabolism. Reactivity studies reveal that the tricopper complex 1 is more efficient than monocopper analogues in catalyzing the hydrolysis of 4-nitrophenyl phosphate.