95388-79-7

Basic information

• Product Name: tert-Butyl 4-chlorobutylcarbamate
• Synonyms: Carbamic acid, (4-chlorobutyl)-, 1,1-dimethylethyl ester (9CI);tert-butyl 4-chlorobutylcarbamate;tert-butyl N-(4-chlorobutyl)carbamate
• CAS NO: 95388-79-7
• Molecular Formula: C₉H₁₈ClNO₂
• Molecular Weight: 207.7
• Product Categories: N-BOC
• Mol File: 95388-79-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 292.9 °C at 760 mmHg
• Flash Point: 130.9 °C
• Appearance: /
• Density: 1.034 g/cm³
• Vapor Pressure: 0.00178mmHg at 25°C
• Refractive Index: 1.449
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 12.78±0.46(Predicted)
• CAS DataBase Reference: tert-Butyl 4-chlorobutylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 4-chlorobutylcarbamate(95388-79-7)
• EPA Substance Registry System: tert-Butyl 4-chlorobutylcarbamate(95388-79-7)

Safety Data

• Hazardous Substances Data: 95388-79-7(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-chlorobutylcarbamate, also known as tBoc-4-chlorobutylcarbamate, is a chemical compound used as a protecting group in organic synthesis. It is derived from tert-butyl isocyanate and 4-chlorobutan-1-ol. The compound is commonly used in the pharmaceutical industry to protect amine functional groups from unwanted reactions during chemical synthesis. It can be easily removed under mild conditions, making it a popular choice for protecting amine groups in peptide synthesis. Additionally, it is used in the production of specialty chemicals and agrochemicals. As with any chemical compound, proper safety precautions should be taken when handling and using tert-butyl 4-chlorobutylcarbamate.

InChI:InChI=1/C9H18ClNO2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7H2,1-3H3,(H,11,12)

Upstream product

• 75844-69-8 t-butyl piperidinecarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 58885-58-8 N-tert-butoxycarbonyl-3-aminopropanol 
• 75178-87-9 (4-hydroxybutyl)carbamic acid tert-butyl ester 
• 75178-90-4 N-(tert-butyloxycarbonyl)-5-aminopentanol 
• 174626-25-6 methanesulfonic acid 4-tert-butoxycarbonylaminobutyl ester 

Relevant articles and documents

DECONSTRUCTIVE FUNCTIONALIZATION METHODS AND COMPOUNDS

Disclosed herein, inter alia, are deconstructive functionalization methods and compounds made using the same.

ORGANIC COMPOUNDS

A compound of formula (I) or tautomers, or stereoisomers, or solvates, or pharmaceutically acceptable salts thereof, wherein M1, M1, L1, L2, W1, W2, X1, X2, Y1, Y2, A, R5 and R5a are as defined herein for the for treatment of conditions mediated by the blockade of an epithelial sodium channel, particularly an inflammatory or allergic condition.

Malonic acid derivatives and methods for their synthesis

The present invention refers to a new class of malonic acid derivatives of general formula I STR1 wherein R1 and R2, each independently, represent hydrogen or a carboxyl protecting group, and the residue R corresponds to the side-cha