959676-13-2

Basic information

• Product Name: 3-benzyloxy-1-thiazolinoethyl-4(1H)-pyridone
• CAS NO: 959676-13-2
• Molecular Weight: 314.408
• Mol File: 959676-13-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyloxy-1-thiazolinoethyl-4(1H)-pyridone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyloxy-1-thiazolinoethyl-4(1H)-pyridone(959676-13-2)
• EPA Substance Registry System: 3-benzyloxy-1-thiazolinoethyl-4(1H)-pyridone(959676-13-2)

Safety Data

• Hazardous Substances Data: 959676-13-2(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 1219-33-6 5-(benzyloxy)-4-oxo-4H-pyran-2-carboxylic acid 
• 15771-06-9 5-benzyloxy-2-hydroxymethyl-4H-pyran-4-one 
• 61049-67-0 3-Benzyloxy-4-pyrone 
• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 156-57-0 2-mercaptoethylamine hydrochloride 

Relevant articles and documents

Synthesis and antimicrobial investigation of thiazolinoalkyl-4(1H)-pyridones

A number of thiazolinoalkyl-4(1H)-pyridones have been synthesized using 4-pyrone derivatives with cysteamine HCI, and their antibacterial and antifungal activities have been tested. Their chemical structures have been proved by means of their IR, 1H-NMR, mass spectroscopic data and by elemental analysis. Investigation of antimicrobial activity of compounds was done by tube dilution and disk tecniques using bacteria (Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Streptococcus faecalis RSKK 10541) and yeast-like fungi (Candida parapsilosis, C albicans, C pseudotropicalis, C stellatoidea). A significant inhibitory effect was recorded for many compounds against C albicans (7a, c, d; minimal inhibitory concentration (MIC) = 12.5-25 μg/ml), S aureus ATCC 25923 (4c, 7a; MIC = 25 μg/ml), P aeruginosa ATCC 27923 (7a; MIC = 75 μg/ml), S faecalis RSKK 10541 (4c; MIC = 25 μg/ml), C pseudotropicalis (46, 6d, 7c; MIC = 25 μg/ml) and C stellatoidea (4d; MIC = 25 μg/ml).