960000-99-1

Basic information

• Product Name: 2-BroMo-4-chloro-5-fluoronitrobenzene
• Synonyms: 2-BroMo-4-chloro-5-fluoronitrobenzene;1-BroMo-5-chloro-4-fluoro-2-nitrobenzene
• CAS NO: 960000-99-1
• Molecular Formula: C₆H₂BrClFNO₂
• Molecular Weight: 254.4409832
• Mol File: 960000-99-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 24-26 °C(Solv: ligroine (8032-32-4); acetone (67-64-1))
• Boiling Point: 255.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.904±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-BroMo-4-chloro-5-fluoronitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-4-chloro-5-fluoronitrobenzene(960000-99-1)
• EPA Substance Registry System: 2-BroMo-4-chloro-5-fluoronitrobenzene(960000-99-1)

Safety Data

• Hazardous Substances Data: 960000-99-1(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-chloro-5-fluoronitrobenzene is a chemical compound categorized within the nitrobenzene group, which contains a nitro group (NO2) and a benzene ring. 2-BroMo-4-chloro-5-fluoronitrobenzene is characterized by the presence of bromine, chlorine, and fluorine atoms as substituents on the benzene ring. It is commonly utilized as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The specific arrangement and positioning of the halogen and nitro groups on the benzene ring determine the compound's reactivity and potential applications in organic synthesis. Additionally, its structural features make it a relevant precursor in the development of advanced materials and biochemical research.

Upstream product

• 104222-34-6 2-nitro-4-fluoro-5-chloroaniline 
• 60811-21-4 1-bromo-3-chloro-4-fluorobenzene 

Downstream Products

• 960001-00-7 methyl 5-[(5-chloro-4-fluoro-2-nitrophenyl)amino]-3-[(phenylmethyl)oxy]-2-thiophenecarboxylate 
• 1185916-54-4 C₁₀H₅ClFNO₂S 
• 960001-03-0 E-Methyl 5-(6-chloro-5-fluoro-1H-benzimidazol-1-yl)-3-{[(1R)-1-{2-chloro-3-hydroxyphenyl)ethyl]oxy}-2-thiophenecarboxylate 
• 960001-01-8 methyl 5-(6-chloro-5-fluoro-1H-benzimidazol-1-yl)-3-[(phenylmethyl)oxy]-2-thiophenecarboxylate 

Relevant articles and documents

Design, synthesis, and fungicidal activity of novel analogues of pyrrolnitrin

A series of novel analogues of pyrrolnitrin containing a thiophene moiety were designed and synthesized by a facile method, and their structures were characterized by 1H nuclear magnetic resonance (NMR) and high-resolution mass spectrometry. The isomers IV-h and V-h were isolated, and their structures were identified by 2D NMR, including heteronuclear multiple-quantum coherence (HMQC), heteronuclear multiple-bond correlation (HMBC), and nuclear Overhauser effect spectrometry (NOESY) spectra. Their fungicidal activities against five fungi were evaluated, and the results indicated that some of the title compounds showed excellent fungicidal activities in vitro against Alternaria solani, Gibberella zeae, Physalospora piricola, Fusarium omysporum, and Cercospora arachidicola at the dosage of 50 μg mL-1. Some compounds shown moderate activity at low dosage. Compound V-h could be considered as a leading structure for further design of agricultural fungicides.

BENZIMIDAZOLE THIOPHENE COMPOUNDS

The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.