96449-14-8

Basic information

• Product Name: BROMOFLUOROACETONITRILE
• Synonyms: BROMOFLUOROACETONITRILE;Bromofluoroacetonitrile 97%;Bromofluoroacetonitrile97%
• CAS NO: 96449-14-8
• Molecular Formula: C2HBrFN
• Molecular Weight: 137.94
• Mol File: 96449-14-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 70.9°Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.865g/cm³
• Vapor Pressure: 127mmHg at 25°C
• Refractive Index: 1.429
• CAS DataBase Reference: BROMOFLUOROACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: BROMOFLUOROACETONITRILE(96449-14-8)
• EPA Substance Registry System: BROMOFLUOROACETONITRILE(96449-14-8)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 96449-14-8(Hazardous Substances Data)

Usage

General Description

Bromofluoroacetonitrile is a chemical compound with the molecular formula C2HBrFNO. It is a colorless liquid with a pungent odor and is primarily used as an intermediate in the synthesis of other organic compounds. Bromofluoroacetonitrile is classified as a halogenated acetonitrile, meaning it contains both bromine and fluorine atoms, which makes it a highly reactive and potentially hazardous chemical. It has been identified as a potential toxicant and can cause irritation to the skin, eyes, and respiratory system. Due to its hazardous nature, proper precautions and safety measures should be taken when handling and storing bromofluoroacetonitrile.

InChI:InChI=1/C2HBrFN/c3-2(4)1-5/h2H

Upstream product

• 401-55-8 ethyl bromofluoroacetate 
• 430-91-1 bromofluoroacetamide 
• 14000-31-8 pyrophosphoric acid 

Relevant articles and documents

A new approach to the synthesis of (Z)-2-fluoro-2-alkenals via Wittig-type carbonyl condensation reactions of 2-(fluoromethyl)-4,4,6-trimethyl-1,3-oxazine phosphonium bromide

We report here the transformation of aldehydes to their (Z)-α-fluoro-α,β-unsaturated aldehyde homologs by condensation with the phosphonium salt of the Meyer's oxazine obtained from bromofluoroacetonitrile. After methylation with trimethyloxonium tetrafluoroborate the quaternized oxazine is cleanly reduced to mostly Z 2-fluoro-2-alkenals by sodium borohydride at room temperature. This methodology is compatible with usual protecting groups and affords an efficient access to functionalized mostly Z 2-fluoro-2-alkenals derived from natural products and their corresponding (Z)-2-fluoro-2-alkenols.

Halonitriles, their preparation and use to make halopyridines

Novel halonitriles, e.g., 2,4-dichloro-2-fluoro-5,5-dimethoxy-4-methylpentanenitrile, method of preparation and use to make halopyridines, some of which are novel, e.g., 2-chloro-3-fluoro-5-methylpyridine. These compounds are intermediates in the preparation of pharmaceutical and agricultural products.