96460-67-2

Basic information

• Product Name: Oxazole, 5-phenyl-2-(2-thienyl)-
• CAS NO: 96460-67-2
• Molecular Formula: C13H9NOS
• Molecular Weight: 227.287
• Mol File: 96460-67-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Oxazole, 5-phenyl-2-(2-thienyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 5-phenyl-2-(2-thienyl)-(96460-67-2)
• EPA Substance Registry System: Oxazole, 5-phenyl-2-(2-thienyl)-(96460-67-2)

Safety Data

• Hazardous Substances Data: 96460-67-2(Hazardous Substances Data)

Upstream product

• 27757-85-3 2-Aminomethylthiophene 
• 70-11-1 α-bromoacetophenone 
• 1400655-60-8 (thiophen-2-yl)formamido 2,2-dimethylpropanoate 
• 536-74-3 phenylacetylene 
• 75690-78-7 N-(2-phenylethyl)thiophene-2-carboxamide 
• 29683-84-9 thiophene-2-carbaldehyde oxime 
• 1393689-93-4 (E)-N-styrylthiophene-2-carboxamide 
• 5813-89-8 2-thiophenylcarboxamide 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 1373758-55-4 3-(thiophen-2-yl)-1,4,2-dioxazole-5-one 
• 2046-39-1 2-thiophenecarbonyl azide 
• 98-03-3 thiophene-2-carbaldehyde 
• 5468-37-1 2-aminoacetophenone hydrochloride 

Downstream Products

• 125061-05-4 5-(5-phenyl-2-oxazolyl)thiophene-2-carboxylic acid 

Relevant articles and documents

Divergent Conversion of N-Acyl-isoxazol-5(2 H)-ones to Oxazoles and 1,3-Oxazin-6-ones Using Photoredox Catalysis

The fragmentation of N-acyl-isoxazol-5-ones using visible light photoredox catalysis has been disclosed. The catalyst-controlled divergent mechanisms, namely the oxidative and reductive quenching catalytic cycle, are utilized. Various oxazoles and 1,3-oxazin-6-ones are selectively obtained from the same isoxazol-5-one skeleton under mild conditions.

Synthesis of 2,5-disubstituted oxazoles: Via cobalt(III)-catalyzed cross-coupling of N -pivaloyloxyamides and alkynes

An efficient synthesis of 2,5-disubstituted oxazoles via Co(iii) catalysis is described herein. The synthesis is achieved under mild conditions through [3+2] cycloaddition of N-pivaloyloxyamides and alkynes. The reaction operates through an internal oxidation pathway and features a very broad substrate scope. The one-step synthesis of natural products such as texamine and balsoxin has been demonstrated via this protocol.

Convenient one-pot synthesis of 2,5-disubstituted oxazoles via a catalytic oxidative dehydrogenation of F3CSO3H·SiO 2-DDQ/CuCl2/LiCl

A facile one-pot synthesis of 2,5-disubstituted oxazoles was developed via cyclization of aldoximes and phenylacetylene then dehydrogenation oxidation. 2,3-dichloro-5,6-dicyano-1,4-benzoquinone was studied for the selective oxidation of oxazolines using Cu2+/Li+ as catalyst and O2 as indirect oxidant. The reaction results showed that this catalyst system can effectively catalyze the oxidation of oxazolines to the corresponding oxazoles. Thus, a variety of polysubstituted oxazoles was easily synthesized in high yields by catalytic oxidation of 2,3-dichloro-5,6-dicyano-1, 4-benzoquinone/CuCl2/LiCl/O2.