97240-80-7 Usage
Description
TopiraMate N-Methyl IMpurity is a chemical substance that occurs as an impurity in Topiramate, an anticonvulsant drug used for treating epilepsy and approved by the FDA for weight loss purposes.
Uses
Used in Pharmaceutical Industry:
TopiraMate N-Methyl IMpurity is used as a reference material for quality control and analytical testing in the development and manufacturing of Topiramate-based medications. This helps ensure the purity, safety, and efficacy of the final drug product.
Used in Research and Development:
TopiraMate N-Methyl IMpurity serves as a valuable compound for researchers studying the properties, mechanisms of action, and potential side effects of Topiramate. Understanding the role of this impurity can contribute to the optimization of drug formulations and the development of safer and more effective treatments for epilepsy and weight loss.
Check Digit Verification of cas no
The CAS Registry Mumber 97240-80-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,2,4 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 97240-80:
(7*9)+(6*7)+(5*2)+(4*4)+(3*0)+(2*8)+(1*0)=147
147 % 10 = 7
So 97240-80-7 is a valid CAS Registry Number.
97240-80-7Relevant articles and documents
Regioselective C(sp3)-H alkylation of a fructopyranose derivative by 1,6-HAT
Li, Yanru,Miyamoto, Shoto,Torigoe, Takeru,Kuninobu, Yoichiro
supporting information, p. 3124 - 3127 (2021/04/21)
Regioselective C(sp3)-H alkylation of a fructopyranose derivative using electron-deficient alkenes as alkylation reagents was achieved. The reaction proceededvia1,6-hydrogen atom transfer under photoredox iridium catalysis. Several functional g
Anticonvulsant O-Alkyl Sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose Sulfamate and Related Compounds.
Maryanoff, Bruce E.,Nortey, Samuel O.,Gardocki, Joseph F.,Shank, Richard P.,Dodgson, Susanna P.
, p. 880 - 887 (2007/10/02)
Novel sugar sulfamate 1 (McN-4853, topiramate) has been found to exhibit potent anticonvulsant activity analogous to that of phenytoin.In the maximal electroshock seizure test, orally at 2 h in mice, 1 had an ED50 of 39 mg/kg.Orally, 1 had a duration of action in excess of 8 h.Other aspects of the pharmacology of 1, as well as neurochemistry and carbonic anhydrase inhibition, are discussed.The conformational behavior of 1 in solution and in the solid state are discussed.A series of analogues of 1 were synthesized and examined for anticonvulsant properties.
