97250-26-5Relevant articles and documents
Rhodium-Catalyzed Remote C(sp3)?H Borylation of Silyl Enol Ethers
Li, Jie,Qu, Shuanglin,Zhao, Wanxiang
supporting information, p. 2360 - 2364 (2020/01/02)
A rhodium-catalyzed remote C(sp3)?H borylation of silyl enol ethers (SEEs, E/Z mixtures) by alkene isomerization and hydroboration is reported. The reaction exhibits mild reaction conditions and excellent functional-group tolerance. This method is compatible with an array of SEEs, including linear and branched SEEs derived from aldehydes and ketones, and provides direct access to a broad range of structurally diverse 1,n-borylethers in excellent regioselectivities and good yields. These compounds are precursors to various valuable chemicals, such as 1,n-diols and aminoalcohols.
Addition reaction of arylboronic acids to aldehydes and α,β-unsaturated carbonyl compounds catalyzed by conventional palladium complexes in the presence of chloroform
Yamamoto, Tetsuya,Iizuka, Michiko,Takenaka, Hiroto,Ohta, Tetsuo,Ito, Yoshihiko
experimental part, p. 1325 - 1332 (2009/09/28)
Arylboronic acids react with aldehydes and α,β-unsaturated carbonyl compounds in the presence of a base and a catalytic amount of a palladium(0) complex with chloroform, affording the corresponding addition products in good yields, and chiral benzhydrol was obtained with up to 43% e.e. using (S,S)-bppm as a ligand. General palladium complexes have no catalytic activity without chloroform. Because chloroform is essential for this reaction, these reactions would be promoted by dichloromethylpalladium(II) species.
Palladium-catalyzed enantioselective conjugate addition of arylboronic acids
Gini, Francesca,Hessen, Bart,Minnaard, Adriaan J.
, p. 5309 - 5312 (2007/10/03)
(Chemical Equation Presented) The first asymmetric palladium-catalyzed conjugate addition of arylboronic acids to α,β-unsaturated aldehydes, ketones, and esters is described. For cyclic substrates, excellent chemo-, regio-, and enantioselectivities are achieved when a Pd(O2CCF 3)2/DuPHOS catalyst is applied.