98555-51-2Relevant articles and documents
HIV INTEGRASE INHIBITORS
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, (2015/09/22)
The present invention features compounds that are HIV integrase inhibitors and therefore are useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.
HIV INTEGRASE INHIBITORS
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Page/Page column 46-47, (2010/11/26)
The present invention features compounds that are HIV integrase inhibitors useful in the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.
Oxidation of 2- and 3-Halogenated Quinolines: An Easy Access to 5- and 6-Halogenopyridine-2,3-dicarboxylic Acids
Bas, Marie-Delphine Le,Gueret, Caroline,Perrio, Cecile,Lasne, Marie-Claire,Barre, Louisa
, p. 2495 - 2499 (2007/10/03)
Pyridine-2,3-dicarboxylic acids bearing an halogen in the position α or β to the nitrogen atom were synthesized by oxidation of the corresponding quinolines. Two methods, using either ozone followed by hydrogen peroxide or ruthenium tetroxide under catalytic conditions were used. Diacids 1b,c and 2a-c substituted in 6-position by a chlorine or bromine and in 5-position by a fluorine, chlorine or bromine, respectively, were isolated in yields ranging from 46-71 percent. Yields of 6-fluoro and 6- or 5-iodo diacids 1a,d and 2d did not exceed 30 percent.