99056-35-6 Usage
General Description
ETHYL 2-METHYL-7-OXO-4,7-DIHYDROPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE is a chemical compound that belongs to the pyrazolo[1,5-a]pyrimidine class. It is an ester of 2-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid. ETHYL 2-METHYL-7-OXO-4,7-DIHYDROPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE has potential pharmaceutical applications as it exhibits various biological activities, including anti-inflammatory and antitumor properties. Its chemical structure contains a pyrazolo[1,5-a]pyrimidine core, making it a valuable intermediate for the synthesis of new drug candidates. Its ethyl ester group allows for easy manipulation and modification of its chemical properties, making it a versatile compound in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 99056-35-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,0,5 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 99056-35:
(7*9)+(6*9)+(5*0)+(4*5)+(3*6)+(2*3)+(1*5)=166
166 % 10 = 6
So 99056-35-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H11N3O3/c1-3-16-10(15)7-5-11-8-4-6(2)12-13(8)9(7)14/h4-5,11H,3H2,1-2H3
99056-35-6Relevant articles and documents
Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB2 cannabinoid receptor inverse agonists
Aghazadeh Tabrizi, Mojgan,Baraldi, Pier Giovanni,Saponaro, Giulia,Moorman, Allan R.,Romagnoli, Romeo,Preti, Delia,Baraldi, Stefania,Ruggiero, Emanuela,Tintori, Cristina,Tuccinardi, Tiziano,Vincenzi, Fabrizio,Borea, Pier Andrea,Varani, Katia
, p. 4482 - 4496 (2013/07/19)
We recently described the medicinal chemistry of a new series of heteroaryl-4-oxopyridine/7-oxopyrimidines as CB2 receptor partial agonists, showing that the functionality of these ligands is controlled by the nature of the heteroaryl function condensed with the pyridine ring. We describe herein the design and synthesis of the 7-oxopyrazolo[1,5-a]pyrimidine-6- carboxamides, structural isomers of our previously reported pyrazolo[3,4-b] pyridines. All of the new compounds showed high affinity and selectivity for the CB2 receptor in the nanomolar range. In 3,5-cyclic adenosine monophosphate (cAMP) assays, the novel series shows stimulatory effects on forskolin-induced cAMP production acting as inverse agonists.
