99725-12-9

Basic information

• Product Name: 2-Fluoro-5-bromobenzyl bromide
• Synonyms: 2-Fluoro-5-bromobenzyl bromide;5-Bromo-2-fluorobenzyl bromide;2-Fluoro-5-broMobenz;4-broMo-2-(broMoMethyl)-1-fluorobenzene;2-fluoro-5-broMobenzyl chloride;2-Fluoro-5-broMobenl broMide;4-Bromo-2-(bromomethyl)-1-fluorobenzene, alpha,5-Dibromo-2-fluorotoluene;5-Bromo-2-fluorobenzyl bromide 97%
• CAS NO: 99725-12-9
• Molecular Formula: C₇H₅Br₂F
• Molecular Weight: 267.92
• Product Categories: Benzyl;Fluorine series;alkyl bromide| alkyl Fluorine
• Mol File: 99725-12-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 253.411 °C at 760 mmHg
• Flash Point: 107.06 °C
• Appearance: /
• Density: 1.923 g/cm³
• Vapor Pressure: 0.029mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Fluoro-5-bromobenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-5-bromobenzyl bromide(99725-12-9)
• EPA Substance Registry System: 2-Fluoro-5-bromobenzyl bromide(99725-12-9)

Safety Data

• Hazardous Substances Data: 99725-12-9(Hazardous Substances Data)

Usage

General Description

2-Fluoro-5-bromobenzyl bromide is a chemical compound with the molecular formula C7H5Br2F. It is a colorless liquid at room temperature and is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. 2-Fluoro-5-bromobenzyl bromide is a benzyl bromide derivative with a fluorine and bromine substituent, making it useful for the tailored modification of molecules in drug development. Its reactivity and ability to form carbon-carbon and carbon-heteroatom bonds make it a versatile compound for the production of intricate organic molecules. It is important to handle and store 2-Fluoro-5-bromobenzyl bromide with caution, as it is considered a hazardous chemical with potential health and environmental risks.

InChI:InChI=1/C7H5Br2F/c8-4-5-3-6(9)1-2-7(5)10/h1-3H,4H2

Upstream product

• 99725-13-0 (5-bromo-2-fluorophenyl)methanol 
• 603-35-0 triphenylphosphine 
• 2094-98-6 1,1'-azobis (cyclohexanecarbonitrile) 
• 51437-00-4 5-bromo-2-fluorotoluene 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 

Downstream Products

• 99748-26-2 2-(acetoxymethyl)-4-bromo-1-fluorobenzene 
• 205055-67-0 3-(S)-(tert-butoxycarbonylamino)-1-(5-bromo-2-fluorobenzyl)pyrrolidin-2-one 
• 728033-28-1 4-(5-bromo-2-fluorophenyl)-butyric acid 
• 728033-48-5 1-(5-benzyloxy-8-formylnaphthalen-1-yloxy)-5-methoxymethoxynaphthalene-4-carbaldehyde 
• 205055-68-1 3-(S)-(tert-butoxycarbonylamino)-1-(5-cyano-2-fluorobenzyl)pyrrolidin-2-one 
• 205055-70-5 5-pyridin-3-ylthiophene-2-sulfonic acid [1-(5-cyano-2-fluorobenzyl)-2-oxopyrrolidin-3-(S)-yl]amide 
• 99725-13-0 (5-bromo-2-fluorophenyl)methanol 
• 99725-14-1 4-bromo-1-fluoro-2-<<<(1,1-dimethylethyl)dimethylsilyl>oxy>methyl>benzene 
• 305800-60-6 2-(5-bromo-2-fluorophenyl)acetonitrile 
• 258886-07-6 4-(5-bromo-2-fluorobenzyl)-5-methoxy-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 
• 942154-51-0 1-(5.bromo-2-fluorobenzyl)-1H-1,2,4-triazole 
• 1262859-92-6 4-bromo-1-fluoro-2-nitromethyl-benzene 

Relevant articles and documents

ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS

The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF

The present application relates to novel carboxylic acid derivatives having an oxo-substituted azaheterocyclic partial structure, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES

The present invention relates to i-benzylindole-2-carboxamide derivatives of formula I, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 1-benzylindole-2-carboxamide deriva