High-performance Liquid Chromatographic Determination of (Z)- and (E)-Doxepin hydrochloride (cas 1229-29-4) Isomers
-
Add time:07/30/2019 Source:sciencedirect.com
A high-performance liquid chromatographic method for the determination of (Z)- and (E)-doxepin hydrochloride isomers was developed. The analysis employs a column packed with spherical silica microparticles (5-6 μm), and a mobile phase of acetonitrile-chloro-form-diethylamine (750:250:0.2) permits baseline resolution and simultaneous determination of the (Z)- and (E)-doxepin isomers. Process-related substances do not interfere. The method is accurate and precise (the relative standard deviation was 0.3% for both isomers). The simple procedure is highly suitable for routine doxepin hydrochloride analysis.
We also recommend Trading Suppliers and Manufacturers of Doxepin hydrochloride (cas 1229-29-4). Pls Click Website Link as below: cas 1229-29-4 suppliers
Prev:Extractive spectrophotometric methods for the determination of Doxepin hydrochloride (cas 1229-29-4) in pharmaceutical preparations using titanium (IV) and iron (III) thiocyanate complexes
Next:Therapeutic rationale for low dose doxepin in insomnia patients) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Transbuccal delivery of doxepin: Studies on permeation and histological investigation08/01/2019
- Therapeutic rationale for low dose doxepin in insomnia patients07/31/2019
- Extractive spectrophotometric methods for the determination of Doxepin hydrochloride (cas 1229-29-4) in pharmaceutical preparations using titanium (IV) and iron (III) thiocyanate complexes07/29/2019
- Highly sensitive LC–MS/MS method to estimate doxepin and its metabolite nordoxepin in human plasma for a bioequivalence study07/28/2019
- Spectroscopic study of charge transfer complexation between doxepin and π–acceptors and its application in quantitative analysis07/27/2019
- Study of the interaction between Doxepin hydrochloride (cas 1229-29-4) and bovine serum albumin by spectroscopic techniques07/26/2019
- Spectrofluorimetric determination of Doxepin hydrochloride (cas 1229-29-4) in commercial dosage forms via ion pair complexation with alizarin red S07/25/2019
-
Health and Chemical more >