Anomalous observations of HYDROCODONE (cas 125-29-1) in patients on oxycodone
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Add time:09/28/2019 Source:sciencedirect.com
BackgroundUrine drug monitoring is used by physicians treating chronic pain patients with opioid therapy. Patients are tested in part to insure that they are not taking other drugs. Therefore, the finding of HYDROCODONE (cas 125-29-1) in a patient who is only prescribed oxycodone has clinical implications. Oxycodone preparations are known to have small amounts of hydrocodone as an impurity estimated to be < 0.1%. We established the concentration of unexpected hydrocodone in patients taking oxycodone.
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