Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
trans-4-Hydroxy-D-proline |
EINECS | 219-963-5 |
CAS No. | 3398-22-9 | Density | 1.395 g/cm3 |
PSA | 69.56000 | LogP | -0.87740 |
Solubility | N/A | Melting Point |
260°C |
Formula | C5H9NO3 | Boiling Point | 355.2 °C at 760 mmHg |
Molecular Weight | 131.131 | Flash Point | 168.6 °C |
Transport Information | N/A | Appearance | White crystal or crystalline powder |
Safety | 24/25-36/37-26 | Risk Codes | 22-36/37/38-43 |
Molecular Structure | Hazard Symbols | Xn | |
Synonyms |
D-Proline,4-hydroxy-, trans-;(2R,4S)-(+)-4-Hydroxy-D-proline;4-(S)-Hydroxypyrrolidine-2-(R)-carboxylic acid;D-Hydroxyproline;D-trans-4-Hydroxyproline;NSC 206273;trans-4-Hydroxy-D-proline; |
Article Data | 9 |
trans-4-hydroxyproline
Conditions | Yield |
---|---|
With ammonia; sodium at -70℃; for 3.5h; Inert atmosphere; | 79% |
N-Acetyl-allo-4-(p-toluenesulfonyloxy)-D-proline
trans-4-hydroxyproline
Conditions | Yield |
---|---|
With sodium hydroxide Erhitzen des Reaktionsprodukts mit wss. HCl; |
trans-1-(3,5-dinitro-benzoyl)-4-hydroxy-D-proline
trans-4-hydroxyproline
Conditions | Yield |
---|---|
With hydrogenchloride | |
With hydrogenchloride |
trans-4-hydroxyproline
Conditions | Yield |
---|---|
With ammonia at 95 - 100℃; |
N-Acetyl-allo-4-(p-toluenesulfonyloxy)-D-proline
trans-4-hydroxyproline
Conditions | Yield |
---|---|
anschliessend Erhitzen mit wss. HCl; |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: aqueous NaOH 2: (1S,2S)-2-amino-1-<4-nitro-phenyl>-propane-1,3-diol 3: aqueous HCl View Scheme | |
Multi-step reaction with 3 steps 1: sodium hydroxide 2: (1S,2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol 3: hydrogenchloride View Scheme |
N-Acetyl-allo-4-(p-toluenesulfonyloxy)-D-proline Methyl Ester
trans-4-hydroxyproline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: aqueous methanol. NaOH 2: aqueous NaOH / Erhitzen des Reaktionsprodukts mit wss. HCl View Scheme |
trans-1-(3,5-dinitro-benzoyl)-4-hydroxy-DL-proline
trans-4-hydroxyproline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: brucine 2: aqueous HCl View Scheme | |
Multi-step reaction with 2 steps 1: (1S,2S)-2-amino-1-<4-nitro-phenyl>-propane-1,3-diol 2: aqueous HCl View Scheme | |
Multi-step reaction with 2 steps 1: (1S,2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol 2: hydrogenchloride View Scheme |
Conditions | Yield |
---|---|
With shaking calcined L-Pro chiral ordered mesoporous silica Resolution of racemate; |
trans-4-hydroxyproline
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 3 h / 0 - 30 °C / Inert atmosphere 2: Jones reagent / acetone / 4 h / 0 °C / Inert atmosphere 3: ammonia; sodium / 3.5 h / -70 °C / Inert atmosphere View Scheme |
Product Categories of trans-4-Hydroxy-D-proline(3398-22-9):Pyrrolidines;Carboxylic Acids;Carboxylic Acids;Chiral Compound