6776-31-4Relevant articles and documents
Catalytic Asymmetric Mannich Type Reaction with Tri-/Difluoro- or Trichloroacetaldimine Precursors
You, Yang'En,Luo, Sanzhong
, p. 7137 - 7140 (2018)
A highly efficient catalytic asymmetric Mannich type reaction of CF3-, CF2H-, or CCl3-acetaldimine precursors by a chiral primary amine is presented. This protocol provides facile access to chiral CF3
A chiral α - amino acid derivative and its preparation method (by machine translation)
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Paragraph 0105; 0106; 0107; 0108, (2018/01/03)
The invention discloses a chiral α - amino acid derivative and its preparation method. The invention α - chiral amino acid derivatives, its structural formula shown in formula I: Its preparation method, comprises the following steps: with the carbonyl compound to the N, O - acetal of the mixture with a chiral primary uncle diamine organic small molecule catalyst, strong and weak acid mixing, reaction, to obtain the chiral α - amino acid compounds; the carbonyl compound including aldehyde and/or ketone. The invention chiral α - amino acid ester compound having a simple structure of the chiral primary uncle diamine organic small molecule catalyst catalytic, solvent-free, one-step synthesis, simple, high-efficiency. (by machine translation)