- 4-Hydroxybenzyl alcohol
- 4-Hydroxybenzyl chloride
- 4-Hydroxybenzyl cyanide
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Cas Database |
| Name |
4-Hydroxybenzyl chloride |
EINECS | N/A |
| CAS No. | 35421-08-0 | Density | 1.233g/cm3 |
| PSA | 20.23000 | LogP | 2.13100 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C7H7 Cl O | Boiling Point | 257.4°Cat760mmHg |
| Molecular Weight | 142.585 | Flash Point | 109.5°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
4-Chloromethylphenol;4-Hydroxybenzyl chloride; p-Chloromethylphenol; p-Hydroxybenzyl chloride; a-Chloro-p-cresol |
Article Data | 9 |
4-Hydroxybenzyl chloride Synthetic route
- 169308-96-7
4-tosyloxy-benzylchloride
- 35421-08-0
4-hydroxybenzyl chloride
| Conditions | Yield |
|---|---|
| With potassium fluoride on basic alumina for 0.05h; Substitution; microwave irradiation; | 83% |
- 39720-27-9
4-acetoxybenzyl chloride
- 35421-08-0
4-hydroxybenzyl chloride
| Conditions | Yield |
|---|---|
| With sodium perborate In methanol at 25℃; for 0.5h; | 81% |
- 623-05-2
(4-hydroxyphenyl)methanol
- 35421-08-0
4-hydroxybenzyl chloride
| Conditions | Yield |
|---|---|
| With tetrachloromethane; potassium fluoride; triphenylphosphine In N,N-dimethyl-formamide at 50℃; for 0.0833333h; Microwave irradiation; | 81% |
| With thionyl chloride In chloroform at 20℃; for 1h; | 48% |
| With 1-chloro-1-(dimethylamino)-2-methyl-1-propene In chloroform at 20℃; Inert atmosphere; |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 2: PCl3, PhCONH2, (PhCO)2O2, SO2Cl2 / 135 °C View Scheme |
- 15451-04-4
p-chloromethyl-phenyl chloroformate
- 35421-08-0
4-hydroxybenzyl chloride
- 937-62-2
p-tolyl chloroformate
- 35421-08-0
4-hydroxybenzyl chloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: PCl3, PhCONH2, (PhCO)2O2, SO2Cl2 / 135 °C View Scheme |
- 15451-04-4
p-chloromethyl-phenyl chloroformate
- 68-12-2, 33513-42-7
N,N-dimethyl-formamide
- 35421-08-0
4-hydroxybenzyl chloride
| Conditions | Yield |
|---|---|
| In methanol; acetonitrile | |
| In methanol; acetonitrile |
- 35421-08-0
4-hydroxybenzyl chloride
- 86087-23-2
(S)-3-hydroxytetyrahydrofurane
| Conditions | Yield |
|---|---|
| Stage #1: 4-hydroxybenzyl chloride In dichloromethane at -5 - 0℃; for 3h; Stage #2: (S)-3-hydroxytetyrahydrofurane With N-ethyl-N,N-diisopropylamine In tetrahydrofuran for 4.5h; Reagent/catalyst; Reflux; | 95.3% |
- 35421-08-0
4-hydroxybenzyl chloride
B
- 3173-38-4
diethyl (4-hydroxybenzyl)phosphonate
| Conditions | Yield |
|---|---|
| In acetonitrile | A n/a B 93% |
| In acetonitrile | A 93% B n/a |
4-Hydroxybenzyl chloride Chemical Properties
IUPAC Name: 4-Hydroxybenzyl chloride
The MF of 4-Hydroxybenzyl chloride (35421-08-0) is C7H7ClO.
The MW of 4-Hydroxybenzyl chloride (35421-08-0) is 142.58.
Synonyms of 4-Hydroxybenzyl chloride (35421-08-0): p-Choro-m-cresol ; p-Hydroxybenzylchloride ; 4-Chloromethylphenol ; 4-Hydroxybenzyl chloride
Index of Refraction: 1.569
Density: 1.233 g/ml
Flash Point: 109.5 °C
Boiling Point: 257.4 °C
4-Hydroxybenzyl chloride Uses
4-Hydroxybenzyl chloride (35421-08-0) is used as pharmaceutical intermediates.
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