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7784-82-9

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PROCESS FOR LARGE SCALE LIQUID PHASE SYNTHESIS OF CARBETOCIN AND ITS NOVEL INTERMEDIATES
A process for large scale liquid phase synthesis of Carbetocin is disclosed. Novel intermediates of formula (A), formula (B), and processes for their preparation are also disclosed.
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Page/Page column 22

(2017/11/06)

PEPTIDE SYNTHESIS BY USING N-ACYLPHOSPHORAMIDITES
New trivalent phosphorus compounds, N-acetyl-N-methylphosphoramidites were prepared readily in good yield by the reaction of phosphorous chlorides and N-methylacetamide.By using the phosphoramidites as condensing agents, Young's peptide and prolyl-leucyl-
Kawanobe, Wataru,Yamaguchi, Kazuo,Nakahama, Seiichi,Yamazaki, Noboru
p. 825 - 828
(2007/10/02)

Sulfonic acid esters
A novel process for the amidation or esterification which comprises reacting a compound having a carboxy group with a compound having an amino or imino group which can be acylated or with a compound having a hydroxy group in the presence of a sulfonic acid ester of the formula: wherein R1 is an organic group and R2 O-- is a residue of a strongly acidic N-hydroxy compound as a condensation agent, and a novel sulfonic acid ester useful as such a condensation agent and a process for the preparation thereof.
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(2008/06/13)

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Chemical Properties

Melting Point: 152-153℃
Boiling Point: 660.5 °C at 760 mmHg
Flash Point:353.3 °C
Density: 1.187 g/cm³
Storage Temp.:-15°C
Vapor Pressure: 2.55E-17mmHg at 25°C
Refractive Index: 1.534
PSA: 114.04000
LogP: 2.71750

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