Use of Strain-Release for the Diastereoselective Construction of Quaternary Carbon Centers
Herein, we describe the formation of quaternary carbon centers with excellent diastereoselectivity via a strain-release protocol. An organometallic species is generated by Cp*Rh(III)-catalyzed C-H activation, which is then coupled with strained bicyclobut
Pinkert, Tobias,Das, Mowpriya,Schrader, Malte L.,Glorius, Frank
supporting information
p. 7648 - 7654
(2021/05/26)
Rhodium(III)-catalyzed coupling of aromatic ketazines or oximes with 2-vinyloxirane via C-H activation
Described herein is a rhodium(III)-catalyzed coupling of aromatic ketazines or oximes with 2-vinyloxirane via directed C-H activation. This reaction proceeds efficiently under mild conditions with a low catalyst loading, especially in conditions with room temperature in the absence of additives for aromatic ketazines. A wide range of substituted substrates is supported and a possible mechanism is proposed according to the experimental results of kinetic isotopic effect, reversibility studies, and catalysis with rhodacycle intermediate c1.
Wen, Jing,Wu, An,Miao, Yuqin,Zhu, Jin
p. 5512 - 5516
(2015/09/21)
Asymmetric reduction of oxime ethers promoted by chiral spiroborate esters with an O3BN framework
Enatioselective reduction of oxime ethers promoted by chiral spiroborate esters with an O3BN framework is reported for the first time. In the presence of (R,S)-1, 11 aralkyloxime ethers are reduced by borane-THF at 0-5 °C to give (S)-1-aralkylamine in high yield and excellent enatiomeric excess (up to 98% ee). Influence of reaction conditions on the enantioselectivity of the reduction is investigated, and a possible mechanism of the catalytic reduction is suggested.
Chu, Yunbo,Shan, Zixing,Liu, Dejun,Sun, Nannan
p. 3998 - 4001
(2007/10/03)
Rates of Acid-Catalyzed Geometric Isomerization of Some Compounds Containing a Carbon-Nitrogen Double Bond
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Johnson, James Elver,Silk, Nancy McPeters,Arfan, Mohammed
p. 1958 - 1961
(2007/10/02)
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