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Name	Difenidol hydrochloride	EINECS	221-850-0
CAS No.	3254-89-5	Density	N/A
PSA	23.47000	LogP	4.12650
Solubility	N/A	Melting Point	212-214°
Formula	C₂₁H₂₇NO^.HCl	Boiling Point	473.3 °C at 760 mmHg
Molecular Weight	345.912	Flash Point	233.5 °C
Transport Information	N/A	Appearance	crystals, soluble in methanol, water
Safety	36	Risk Codes	20/21/22
Molecular Structure		Hazard Symbols	Xn
Synonyms	Ansmin;Cefadol;Celmidol;Difenidolin;Maniol;Mecalmin;Pineroro;SKF 478A;Satanolon;Tenesdol;Vontrol;Wansar;	Article Data	2

Difenidol hydrochloride Chemical Properties

CEFADOL 's Molecular Formula: C₂₁H₂₇NO.HCl
CEFADOL 's Molecular Weight: 345.91
EINECS: 221-850-0
Synonyms: Difenidol hydrochloride;1,1-Diphenyl-4-(1-piperidyl)butan-1-ol hydrochloride

Difenidol hydrochloride Uses

CEFADOL is used as antiemetic.

Difenidol hydrochloride Toxicity Data With Reference

1.	orl-rat LD50:515 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
2.	ipr-rat LD50:82 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
3.	scu-rat LD50:670 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
4.	ivn-rat LD50:29 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
5.	ims-rat LD50:635 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
6.	orl-mus LD50:400 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
7.	ipr-mus LD50:105 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
8.	scu-mus LD50:163 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
9.	ivn-mus LD50:37 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.

Difenidol hydrochloride Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by intramuscular route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and HCl.

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