Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
L-Ornithine |
EINECS | 200-731-7 |
CAS No. | 70-26-8 | Density | 1.165 g/cm3 |
PSA | 89.34000 | LogP | 0.53780 |
Solubility | soluble in water and ethanol, slightly soluble in diethyl ether | Melting Point |
140 °C |
Formula | C5H12N2O2 | Boiling Point | 308.718 °C at 760 mmHg |
Molecular Weight | 132.162 | Flash Point | 140.508 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | R23/25; R33; R50/53 | |
Molecular Structure | Hazard Symbols | T,N | |
Synonyms |
Ornithine,L- (8CI);(+)-S-Ornithine;(S)-2,5-Diaminopentanoic acid;(S)-Ornithine;(S)-a,d-Diaminovaleric acid;L-(-)-Ornithine;L-Norvaline,5-amino-;Ornithine;Pentanoic acid, 2,5-diamino-, (S)-; |
Article Data | 149 |
cyclo(-Orn(Boc)-L-Ala-)
L-ornithine
Conditions | Yield |
---|---|
With hydrogenchloride at 110℃; for 24h; | 62% |
Conditions | Yield |
---|---|
With calcium hydroxide In ethanol at 50℃; for 1.5h; Product distribution / selectivity; | 43.95% |
With acidic ion exchange resin (Marason C, H-type) In water Product distribution / selectivity; |
glucose
L-ornithine
Conditions | Yield |
---|---|
mit Hilfe von Mutanten von Micrococcus glutamicus; |
Conditions | Yield |
---|---|
bei der Einw. von Leberpresssaft; | |
With barium dihydroxide | |
With arginase |
Conditions | Yield |
---|---|
With mammal liver | |
With barium dihydroxide | |
With urease; arginase |
N2-(toluene-4-sulfonyl)-L-ornithine
L-ornithine
Conditions | Yield |
---|---|
With hydrogen bromide; acetic acid |
N-(toluene-4-sulfonyl)-L-glutamic acid-5-nitrile
L-ornithine
Conditions | Yield |
---|---|
With methanol; ammonia; sodium | |
Multi-step reaction with 2 steps 1: platinum; acetic acid; aqueous HCl / Hydrogenation 2: HBr; acetic acid View Scheme |
Conditions | Yield |
---|---|
mit Hilfe von Mutanten von Micrococcus glutamicus; |
L-ornithine
Conditions | Yield |
---|---|
With ammonium hydroxide |
Reported in EPA TSCA Inventory.
The L-Ornithine, with the CAS registry number 70-26-8, is also known as (S)-2,5-Diaminopentanoic acid. It belongs to the product categories of Amino Acids; Nutritional Supplements. Its EINECS number is 200-731-7. This chemical's molecular formula is C5H12N2O2 and molecular weight is 132.16. What's more, its systematic name is L-L-Ornithine. Its classification code is Mutation data. L-Ornithine is an amino acid that plays a role in the urea cycle. It is abnormally accumulated in the body in L-Ornithine transcarbamylase deficiency.
Physical properties of L-Ornithine are: (1)ACD/LogP: -0.874; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -4.37; (4)ACD/LogD (pH 7.4): -4.28; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 4; (10)#H bond donors: 5; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 89.34 Å2; (13)Index of Refraction: 1.508; (14)Molar Refractivity: 33.807 cm3; (15)Molar Volume: 113.426 cm3; (16)Polarizability: 13.402×10-24cm3; (17)Surface Tension: 54.6 dyne/cm; (18)Density: 1.165 g/cm3; (19)Flash Point: 140.508 °C; (20)Enthalpy of Vaporization: 60.423 kJ/mol; (21)Boiling Point: 308.718 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.
Preparation of L-Ornithine: this chemical can be prepared by cyclo(-Orn(Boc)-L-Ala-) at the temperature of 110 °C. This reaction will need reagent 6M HCl with the reaction time of 24 hours. The yield is about 62%.
Uses of L-Ornithine: it can be used to produce N,N-bis(methoxycarbonyl)-L-L-Ornithine at the temperature of 20 °C. It will need reagent aq. NaHCO3 and solvent tetrahydrofuran. The yield is about 86%.
You can still convert the following datas into molecular structure:
(1)SMILES: O=C(O)[C@@H](N)CCCN
(2)Std. InChI: InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
(3)Std. InChIKey: AHLPHDHHMVZTML-BYPYZUCNSA-N