2-amino-9H-thioxanthen-9-one

Base Information

• Chemical Name: 2-amino-9H-thioxanthen-9-one
• CAS No.: 33923-98-7
• Molecular Formula: C13H9NOS
• Molecular Weight: 227.287
• Hs Code.: 2932999099
• Mol file: 33923-98-7.mol

Synonyms:2-aminothioxanthen-9-one;2-Amino-thioxanthen-9-on;2-aminothioxanthone;2-amino-9H-thioxanthen-9-one;

Chemical Property of 2-amino-9H-thioxanthen-9-one

Chemical Property:

• PSA: 71.33000
• LogP: 3.57810

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-9H-thioxanthen-9-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-amino-9H-thioxanthen-9-one

There total 18 articles about 2-amino-9H-thioxanthen-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-Nitro-9,10-thiaxanthenone (72534-70-4) → 2-amino-9H-thioxanthen-9-one (33923-98-7)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; for 3h; Heating;

DOI:10.1002/jhet.5570360336

Reference yield: 80.0%

2-Chlorothioxanthone (86-39-5) → 2-amino-9H-thioxanthen-9-one (33923-98-7)

Guidance literature:

With dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C₅₀H₇₀NO₄PPdS; C₅₀H₇₀NO₄PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate; In 1,4-dioxane; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol401612c

Reference yield: 70.0%

→ 2-amino-9H-thioxanthen-9-one (33923-98-7)

Guidance literature:

With ammonium hydroxide; potassium phosphate; copper(l) iodide; N¹,N²-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide; In dimethyl sulfoxide; at 110 ℃; for 24h; Inert atmosphere; Schlenk technique;

upstream raw materials:

2-Nitro-9,10-thiaxanthenone

2-(4-amino-phenylsulfanyl)-benzoic acid

2-(4-amino-phenylsulfanyl)-benzoic acid benzenesulfonylamide

meta-aminobenzoic acid

Downstream raw materials:

2-Chlorothioxanthone

2-bromothioxanthone

1-(9-Oxo-9H-thioxanthen-2-yl)-3-p-tolyl-thiourea

1-(9-Oxo-9H-thioxanthen-2-yl)-3-phenyl-thiourea

Refernces

• 1、 Fan, Mengyang,Zhou, Wei,Jiang, Yongwen,Ma, Dawei. "Assembly of Primary (Hetero)Arylamines via CuI/Oxalic Diamide-Catalyzed Coupling of Aryl Chlorides and Ammonia". supporting information. p. 5934 - 5937. Retrieved 2015/12/11.
• 2、 Cheung, Chi Wai,Surry, David S.,Buchwald, Stephen L.. "Mild and highly selective palladium-catalyzed monoarylation of ammonia enabled by the use of bulky biarylphosphine ligands and palladacycle precatalysts". supporting information. p. 3734 - 3737. Retrieved 2013/08/23.