86-39-5Relevant articles and documents
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Muren,Bloom
, p. 14,16 (1970)
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Oxidation of chlorprothixene with ceric sulphate.
Agarwal,Blake
, p. 556 - 556 (1969)
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Catalyst-Controlled Stereoselective Barton–Kellogg Olefination
Schmidt, Tanno A.,Sparr, Christof
supporting information, p. 23911 - 23916 (2021/10/08)
Overcrowded alkenes are expeditiously prepared by the versatile Barton–Kellogg olefination and have remarkable applications as functional molecules owing to their unique stereochemical features. The induced stereodynamics thereby enable the controlled motion of molecular switches and motors, while the high configurational stability prevents undesired isomeric scrambling. Bistricyclic aromatic enes are prototypical overcrowded alkenes with outstanding stereochemical properties, but their stereocontrolled preparation was thus far only feasible in stereospecific reactions and with chiral auxiliaries. Herein we report that direct catalyst control is achieved by a stereoselective Barton–Kellogg olefination with enantio- and diastereocontrol for various bistricyclic aromatic enes. Using Rh2(S-PTAD)4 as catalyst, several diazo compounds were selectively coupled with a thioketone to give one of the four anti-folded overcrowded alkene stereoisomers upon reduction. Complete stereodivergence was reached by catalyst control in combination with distinct thiirane reductions to provide all four stereoisomers with e.r. values of up to 99:1. We envision that this strategy will enable the synthesis of topologically unique overcrowded alkenes for functional materials, catalysis, energy- and electron transfer, and bioactive compounds.
Ultraviolet light promoted synthesis method of thioxanthone compounds
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Paragraph 0029-0030, (2020/06/02)
The invention discloses an ultraviolet light promoted synthesis method of a thioxanthone compound. The preparation method comprises the following steps: carrying out a reaction in 1,2-dichloroethane at normal temperature under the condition of 380-385 nm ultraviolet irradiation by taking a thioxanthone compound as a reaction substrate and taking oxygen in air as an oxidizing agent, and after the reaction is finished, carrying out separation treatment to obtain the thioxanthone compound. According to the synthesis method disclosed by the invention, the traditional heating reaction is replaced by an illumination reaction, so that energy sources can be saved, and any catalyst is not used.