N-(2,2-Dimethoxyethyl)methacrylamide

Base Information

• Chemical Name: N-(2,2-Dimethoxyethyl)methacrylamide
• CAS No.: 95984-11-5
• Molecular Formula: C8H15NO3
• Molecular Weight: 173.212
• Hs Code.: 2924199090
• European Community (EC) Number: 306-091-6
• DSSTox Substance ID: DTXSID90242058
• Nikkaji Number: J382.880H
• Wikidata: Q72467944
• Mol file: 95984-11-5.mol

Synonyms:N-(2,2-Dimethoxyethyl)methacrylamide;95984-11-5;N-(2,2-dimethoxyethyl)-2-methylprop-2-enamide;N-(2,2-Dimethoxyethyl)-2-methylpropenamide;EINECS 306-091-6;2-Propenamide, N-(2,2-dimethoxyethyl)-2-methyl-;N-(2,2-Dimethoxyethyl)-2-methylacrylamide;SCHEMBL136474;DTXSID90242058;MGARLISKINLYPI-UHFFFAOYSA-N;MFCD13152039;AKOS027276408;methacrylamidoacetaldehyde dimethylacetal;N-(2, 2-dimethoxyethyl)methacrylamide;methacrylamido acetaldehyd-dimethylacetal;AS-62542;CS-0059721;N10030;A1-06641

Chemical Property of N-(2,2-Dimethoxyethyl)methacrylamide

Chemical Property:

• Vapor Pressure: 0.000899mmHg at 25°C
• Refractive Index: 1.437
• Boiling Point: 304 °C at 760mmHg
• PKA: 14.84±0.46(Predicted)
• Flash Point: 137.6 °C
• PSA: 47.56000
• Density: 0.992 g/cm³
• LogP: 0.68850
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 173.10519334
• Heavy Atom Count: 12
• Complexity: 164

Purity/Quality:

99% ^*data from raw suppliers

N-(2,2-Dimethoxyethyl)methacrylamide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)C(=O)NCC(OC)OC

Technology Process of N-(2,2-Dimethoxyethyl)methacrylamide

There total 2 articles about N-(2,2-Dimethoxyethyl)methacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methacrylic acid N-hydroxysuccinimide ester (38862-25-8) + 2,2-dimethoxyethylamine (22483-09-6) → methacrylamidoacetaldehyde dimethyl acetal (95984-11-5)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 72h;

Reference yield:

2,2-dimethoxyethylamine (22483-09-6) + Methacryloyl chloride (920-46-7,26937-45-1) → methacrylamidoacetaldehyde dimethyl acetal (95984-11-5)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hydroxide; In water; at 20 ℃; for 26h; Inert atmosphere;

DOI:10.1039/c3cc48514e

upstream raw materials:

2,2-dimethoxyethylamine

Methacryloyl chloride

methacrylic acid N-hydroxysuccinimide ester

Refernces

• 1、 -. "POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF". Paragraph 0189. . Retrieved 2016/06/28.
• 2、 Patenaude, Mathew,Campbell, Scott,Kinio, Dennis,Hoare, Todd. "Tuning gelation time and morphology of injectable hydrogels using Ketone-Hydrazide cross-linking". . p. 781 - 790. Retrieved 2014/04/03.