2,5-DibroMo-1,4-benzenediMethanol

Base Information

• Chemical Name: 2,5-DibroMo-1,4-benzenediMethanol
• CAS No.: 395059-21-9
• Molecular Formula: C8H8Br2O2
• Molecular Weight: 295.958
• Mol file: 395059-21-9.mol

Synonyms:2,5-Dibromo-1,4-benzenedimethanol;1,4-Benzenedimethanol,2,5-dibromo;2,5-dibromo-1,4-di(hydroxymethyl)benzene;

Chemical Property of 2,5-DibroMo-1,4-benzenediMethanol

Chemical Property:

• Melting Point: 217-218℃
• Boiling Point: 419.1±40.0 °C(Predicted)
• PKA: 13.47±0.10(Predicted)
• PSA: 40.46000
• Density: 1.980
• LogP: 2.19620

Purity/Quality:

99% ^*data from raw suppliers

(2,5-Dibromo-1,4-phenylene)dimethanol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-DibroMo-1,4-benzenediMethanol

There total 4 articles about 2,5-DibroMo-1,4-benzenediMethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,5-dibromoterephthalaldehyde (63525-48-4) → 2,5-dibromo-1,4-di(hydroxymethyl)benzene (395059-21-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2h;

DOI:10.1055/s-2006-947327

Reference yield:

2,5-dibromo-p-xylene (1074-24-4) → 2,5-dibromo-1,4-di(hydroxymethyl)benzene (395059-21-9)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃

2: NaBH₄

With chromium(VI) oxide; sodium tetrahydroborate;

DOI:10.1021/ma0506132

Reference yield:

acetic acid 4-acetoxymethyl-2,5-dibromo-benzyl ester (4845-68-5) → 2,5-dibromo-1,4-di(hydroxymethyl)benzene (395059-21-9)

Guidance literature:

With sodium hydroxide; In ethanol;

DOI:10.1021/ma030093f

upstream raw materials:

acetic acid 4-acetoxymethyl-2,5-dibromo-benzyl ester

2,5-dibromoterephthalaldehyde

2,5-dibromo-p-xylene

1,4-bis(bromomethyl)-2,5-dibromobenzene

Downstream raw materials:

2,5-Dibromo-7,7,8,8-tetracyano-p-quinodimethane

Dicyano-[2,5-dibromo-4-(dicyano-methoxycarbonyl-methyl)-phenyl]-acetic acid methyl ester

1,4-dibromo-2,5-di(cyanomethyl)benzene

C₈₈H₁₁₄O₆

Refernces

• 1、 Gegout, Aline,Holler, Michel,Figueira-Duarte, Teresa M.,Nierengarten, Jean-Francois. "Synthesis of oligophenylenevinylene heptamers substituted with fullerene moieties". experimental part. p. 3627 - 3634. Retrieved 2009/04/07.
• 2、 Fan, Qu-Li,Lu, Su,Lai, Yee-Hing,Hou, Xiao-Yuan,Huang, Wei. "Synthesis, characterization, and fluorescence quenching of novel cationic phenyl-substituted poly(p-phenylenevinylene)s". . p. 6976 - 6984. Retrieved 2007/10/03.