2-Methyl-1H-indene

Base Information

• Chemical Name: 2-Methyl-1H-indene
• CAS No.: 2177-47-1
• Molecular Formula: C10H10
• Molecular Weight: 130.189
• Hs Code.: 2902909090
• UNII: 22LC0EG9LP
• DSSTox Substance ID: DTXSID00176173
• Nikkaji Number: J20.938D
• Wikidata: Q27253655
• Mol file: 2177-47-1.mol

Synonyms:2-METHYL-1H-INDENE;2-Methylindene;2177-47-1;1H-Indene, 2-methyl-;22LC0EG9LP;MFCD00274253;Indene, 2-methyl-;2-methylinden;2-Methylindene, 98%;UNII-22LC0EG9LP;DTXSID00176173;2-methyl-1H-indene;AC7927;AKOS015914346;AM84769;CS-W021717;DS-17649;SY037985;FT-0634097;A815658;J-014281;Q27253655;2-Benzamido-3-(4-(N,N-bis(2-chloroethyl)amino)phenyl)propionicacid

Chemical Property of 2-Methyl-1H-indene

Chemical Property:

• Appearance/Colour: transparent to yellow liquid
• Vapor Pressure: 0.356mmHg at 25°C
• Melting Point: 80°C
• Refractive Index: n20/D 1.567(lit.)
• Boiling Point: 205.567 °C at 760 mmHg
• Flash Point: 70.76 °C
• PSA: 0.00000
• Density: 1.003 g/cm³
• LogP: 2.64600
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 130.078250319
• Heavy Atom Count: 10
• Complexity: 155

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Methylindene 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC2=CC=CC=C2C1

Technology Process of 2-Methyl-1H-indene

There total 78 articles about 2-Methyl-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2,3-dihydro-2-methyl-1H-inden-1-one (17496-14-9) → 2-Methylindene (2177-47-1)

Guidance literature:

With toluene-4-sulfonic acid; 2,2-Dimethyl-1,3-propanediol; In toluene; for 24h; Reflux;

DOI:10.3184/030823410X12753214605445

Reference yield: 90.0%

2-methylene-2,3-dihydro-1H-indene (68846-65-1) → 2-Methylindene (2177-47-1)

Guidance literature:

With hydrogen bromide; In acetonitrile; for 1h; Heating;

DOI:10.1021/jo00272a006

Reference yield: 88.0%

2-bromoindene (10485-09-3) + [3-(dimethylamino)propyl]dimethyl aluminium(III) → 2-Methylindene (2177-47-1) + 1,2-dimethylindene (70063-93-3) + 1-indene (95-13-6)

Guidance literature:

With tetrakis(triphenylphosphine)palladium dichloride; In benzene; at 80 ℃; for 2h; Yields of byproduct given;

DOI:10.1021/jo970822n

upstream raw materials:

naphthalene-2-sulfonate

2-hydroxy-2-methylindan

(+/-)-cis-1-Acetoxy-2-methyl-indan

(+/-)-trans-1-Acetoxy-2-methyl-indan

Downstream raw materials:

3-methylisoquinoline

1-Methylinden

3-Methylindene

1-indene

Refernces

• 1、 Adam,Casades,Fornes,Garcia,Weichold. "UV-vis and IR spectral characterization of persistent carbenium ions, generated upon incorporation of cinnamyl alcohols in the acid zeolites HZSM-5 and HMor". . p. 3947 - 3951. Retrieved 2000.
• 2、 Palensky,F.J.,Morrison,H.A.. "-". . p. 3507 - 3508. Retrieved 1977.
• 3、 Suarez, Marie L.,Duguid, Robert J.,Morrison, Harry. "Photochemistry of Alkylindenes in the Gas Phase". . p. 6384 - 6391. Retrieved 1989.
• 4、 Yanagisawa, Hideyuki,Miura, Kasei,Kitamura, Mitsuru,Narasaka, Koichi,Ando, Kaori. "Intramolecular substitution reaction of alkylidene-lithium carbenoids: Regioselective synthesis of indenes". . p. 3130 - 3135. Retrieved 2002.
• 5、 Azizi, Kobra,Madsen, Robert. "Radical condensation between benzylic alcohols and acetamides to form 3-arylpropanamides". . p. 7800 - 7806. Retrieved 2020/08/14.
• 6、 Wu, Ji-Cheng,Gong, Lu-Bing,Xia, Yuanzhi,Song, Ren-Jie,Xie, Ye-Xiang,Li, Jin-Heng. "Nickel-catalyzed Kumada reaction of tosylalkanes with Grignard reagents to produce alkenes and modified arylketones". supporting information. p. 9909 - 9913. Retrieved 2012/10/30.