2-ETHOXYPHENYLACETONITRILE

Base Information

• Chemical Name: 2-ETHOXYPHENYLACETONITRILE
• CAS No.: 74205-51-9
• Molecular Formula: C10H11NO
• Molecular Weight: 161.203
• Hs Code.: 2926909090
• Mol file: 74205-51-9.mol

Synonyms:2-Ethoxybenzylcyanide;(2-ethoxyphenyl)acetonitrile;benzeneacetonitrile, 2-ethoxy-;

Chemical Property of 2-ETHOXYPHENYLACETONITRILE

Chemical Property:

• Vapor Pressure: 0.00732mmHg at 25°C
• Melting Point: 32-34°C
• Refractive Index: 1.514
• Boiling Point: 269.3 °C at 760 mmHg
• Flash Point: 112.8 °C
• PSA: 33.02000
• Density: 1.032 g/cm³
• LogP: 2.15138
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-Ethoxyphenyl)acetonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ETHOXYPHENYLACETONITRILE

There total 9 articles about 2-ETHOXYPHENYLACETONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethoxybenzyl alcohol (71672-75-8) → 2-ethoxy benzylcyanide (74205-51-9)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene; hydrogen chloride

2: acetone

With hydrogenchloride; acetone; benzene;

Reference yield:

2-ethoxybenzonitrile (6609-57-0) → 2-ethoxy benzylcyanide (74205-51-9)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium hydroxide; ethylene glycol / Heating

2: lithium aluminium tetrahydride

3: thionyl chloride

4: dimethyl sulfoxide

With lithium aluminium tetrahydride; thionyl chloride; ethylene glycol; potassium hydroxide; In dimethyl sulfoxide;

DOI:10.1002/bkcs.10900

Reference yield:

2-ethoxybenzoic acid (134-11-2) → 2-ethoxy benzylcyanide (74205-51-9)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride

2: thionyl chloride

3: dimethyl sulfoxide

With lithium aluminium tetrahydride; thionyl chloride; In dimethyl sulfoxide;

DOI:10.1002/bkcs.10900

upstream raw materials:

1-chloromethyl-2-ethoxybenzene

potassium cyanide

acetic anhydride

salicylic alcohol

Downstream raw materials:

2'-ethoxy-2,4-dihydroxy-deoxybenzoin

1-(2-Ethoxy-phenyl)-cyclopentanecarbonitrile

5-(2-Ethoxy-benzyl)-1H-tetrazole

1-(2-Ethoxy-phenyl)-cyclopropanecarbonitrile

Refernces