4-Methoxy-N-pentylaniline

Base Information

• Chemical Name: 4-Methoxy-N-pentylaniline
• CAS No.: 882-42-8
• Molecular Formula: C12H19NO
• Molecular Weight: 193.289
• DSSTox Substance ID: DTXSID40582911
• Nikkaji Number: J2.858.320F
• Wikidata: Q82474418
• Mol file: 882-42-8.mol

Synonyms:4-METHOXY-N-PENTYLANILINE;882-42-8;SCHEMBL11331749;DTXSID40582911;AKOS000259111;CS-0297596;EN300-165269

Chemical Property of 4-Methoxy-N-pentylaniline

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 193.146664230
• Heavy Atom Count: 14
• Complexity: 130

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCNC1=CC=C(C=C1)OC

Technology Process of 4-Methoxy-N-pentylaniline

There total 12 articles about 4-Methoxy-N-pentylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%

→ N-(4-methoxy-phenyl)-N-pentyl-amine (882-42-8)

Guidance literature:

Reference yield: 99.0%

para-iodoanisole (696-62-8) + n-Pentylamine (110-58-7) → N-(4-methoxy-phenyl)-N-pentyl-amine (882-42-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 6h; Inert atmosphere;

DOI:10.1002/ejoc.201000149

Reference yield: 83.0%

N-(4-methoxyphenyl)pentanethioamide (35228-40-1) → N-(4-methoxy-phenyl)-N-pentyl-amine (882-42-8)

Guidance literature:

With 4-dimethylaminopyridine borane; di-tert-butoxydiazene; thiophenol; In toluene; at 80 ℃;

DOI:10.1021/acs.orglett.7b03201

upstream raw materials:

amyl iodide

4-methoxy-aniline

para-iodoanisole

n-Pentylamine

Refernces

• 1、 -. "Method for reducing thioamide compound". Paragraph 0027; 0032-0034. . Retrieved 2017/10/07.
• 2、 Verho, Oscar,Gustafson, Karl P. J.,Nagendiran, Anuja,Tai, Cheuk-Wai,B?ckvall, Jan-E.. "Mild and selective hydrogenation of nitro compounds using palladium nanoparticles supported on amino-functionalized mesocellular foam". . p. 3153 - 3159. Retrieved 2015/02/03.