1-(dichloromethyl)-2-methylbenzene

Base Information

• Chemical Name: 1-(dichloromethyl)-2-methylbenzene
• CAS No.: 60973-59-3
• Molecular Formula: C8H8Cl2
• Molecular Weight: 175.058
• Hs Code.: 2903999090
• Mol file: 60973-59-3.mol

Synonyms:bis-chloromethyltoluene;a,a-Dichloro-ortho-xylene;o-methylbenzylidene chloride;ortho-dichloro-xylene;1-dichloromethyl-2-methylbenzene;Benzene,1-(dichloromethyl)-2-methyl;

Chemical Property of 1-(dichloromethyl)-2-methylbenzene

Chemical Property:

• Vapor Pressure: 0.122mmHg at 25°C
• Boiling Point: 226.5°Cat760mmHg
• Flash Point: 99.9°C
• PSA: 0.00000
• Density: 1.202g/cm³
• LogP: 3.47120

Purity/Quality:

97% ^*data from raw suppliers

1-(DICHLOROMETHYL)-2-METHYLBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(dichloromethyl)-2-methylbenzene

There total 5 articles about 1-(dichloromethyl)-2-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-methylphenyl aldehyde (529-20-4) → α,α-dichloro-o-xylene (60973-59-3)

Guidance literature:

With tetrachloromethane; nickel; copper; In N,N-dimethyl-formamide; at 60 ℃; for 5h;

DOI:10.1080/00397919908085922

Reference yield: 50.5%

o-xylene (95-47-6) → o-Xylylene dichloride (612-12-4) + α,α,α'-trichloro-o-xylene (30293-58-4) + α,α-dichloro-o-xylene (60973-59-3) + 1-chloromethyl-2-methylbenzene (552-45-4)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); chlorine; at 90 ℃; for 4h;

Reference yield:

tungsten(VI) chloride (13283-01-7) + 2-methylphenyl aldehyde (529-20-4) → C8H8Cl4O2W (1428885-06-6) + α,α-dichloro-o-xylene (60973-59-3)

Guidance literature:

In dichloromethane; at 20 ℃; for 168h; Sealed tube;

DOI:10.1039/c2dt32771f

upstream raw materials:

o-xylene

2-methylphenyl aldehyde

2-methylphenyl bromide

tungsten(VI) chloride

Downstream raw materials:

benzocyclobutene-1-carboxaldehyde

1-Acetyl-benzocyclobuten

1,2-dihydrocyclobutabenzene-1-carboxylic acid

1-chloro-1,2-dihydrobenzocyclobutene

Refernces

• 1、 Dolci, Sara,Marchetti, Fabio,Pampaloni, Guido,Zacchini, Stefano. "A crystallographic and spectroscopic study on the reactions of WCl 6 with carbonyl compounds". . p. 5635 - 5648. Retrieved 2013/06/05.
• 2、 -. "Process for producing isochromanones and intermediates thereof". Example 14. . Retrieved 2008/06/13.