1,2-Bis(chloromethyl)benzene

Base Information Edit

Chemical Name:1,2-Bis(chloromethyl)benzene
CAS No.:612-12-4
Molecular Formula:C8H8Cl2
Molecular Weight:175.058
Hs Code.:29036990
European Community (EC) Number:210-291-8
NSC Number:71934
DSSTox Substance ID:DTXSID7052284
Nikkaji Number:J1.658F
Wikidata:Q62018667
ChEMBL ID:CHEMBL3561068
Mol file:612-12-4.mol

Synonyms:1,2-Bis(chloromethyl)benzene;612-12-4;alpha,alpha'-Dichloro-o-xylene;o-Xylylene dichloride;o-Bis(chloromethyl)benzene;Benzene, 1,2-bis(chloromethyl)-;12-Bis(chloromethyl)benzene;CCRIS 1773;EINECS 210-291-8;NSC 71934;o-XYLENE, alpha,alpha'-DICHLORO-;BRN 2043675;AI3-16046;DTXSID7052284;.alpha.,.alpha.'-Dichloro-o-xylene;4-05-00-00927 (Beilstein Handbook Reference);MFCD00000903;o-Xylylenchlorid;NSC71934;o-Xylylene Chloride;alpha,alpha'-dichloro xylene;2-chloromethylbenzyl chloride;Benzene,2-bis(chloromethyl)-;o-Xylene,.alpha.'-dichloro-;SCHEMBL150237;CHEMBL3561068;DTXCID7030856;AMY7003;I+/-,I+/-'-dichloro-o-xylene;.alpha.,.alpha.-Dichloro-o-xylene;alpha , alpha '-Dichloro-o-xylene;Tox21_303964;NSC-71934;AKOS009157985;alpha,alpha'-Dichloro-o-xylene, 98%;FS-4096;o-Xylene, .alpha.,.alpha.'-dichloro-;NCGC00357194-01;CAS-612-12-4;LS-162600;A8496;D0429;FT-0606303;EN300-51315;E75751;A833100;AC-509/25002089;W-105177;F0001-1608;alpha,alpha'-Dichloro-o-xylene, purum, >=98.0% (GC), white to light beige

Suppliers and Price of 1,2-Bis(chloromethyl)benzene

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α,α''-Dichloro-o-xylene
25g
$ 55.00

TCI Chemical
α,α'-Dichloro-o-xylene
500G
$ 196.00

TCI Chemical
α,α'-Dichloro-o-xylene
25G
$ 44.00

Sigma-Aldrich
α,α′-Dichloro-o-xylene 98%
100g
$ 110.00

Sigma-Aldrich
α,α′-Dichloro-o-xylene 98%
25g
$ 44.50

Medical Isotopes, Inc.
1,2-Bis(chloromethyl)benzene 98%
100 g
$ 390.00

Matrix Scientific
o-Xylylene dichloride 95%+
5g
$ 323.00

Matrix Scientific
o-Xylylene dichloride 95%+
2.500g
$ 215.00

Matrix Scientific
o-Xylylene dichloride 95%+
1g
$ 101.00

Frontier Specialty Chemicals
alpha,alpha'-Dichloro-o-xylene 97%
100g
$ 90.00

Total 86 raw suppliers

Chemical Property of 1,2-Bis(chloromethyl)benzene Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Melting Point:51-55 °C(lit.)
Refractive Index:1.5544 (estimate)
Boiling Point:239.5 °C at 760 mmHg
Flash Point:114.1 °C
PSA：0.00000
Density:1.208 g/cm³
LogP:3.16420
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:soluble in Methanol
Water Solubility.:hydrolysis
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:174.0003056
Heavy Atom Count:10
Complexity:81.3

Purity/Quality:

99.9% ^*data from raw suppliers

α,α''-Dichloro-o-xylene ^*data from reagent suppliers

Safty Information:

Pictogram(s): C, Xi
Hazard Codes:C,Xi
Statements: 34-36/37-36/37/38-50/53-26-22-36
Safety Statements: 26-27-28-36/37/39-45-24/25-61-29-28A

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CCl)CCl
Uses 1,2-Bis(chloromethyl)benzene is used in solid-phase synthesis of large combinatorial variations of fundamental peptide unit 1 . α,α′?Dichloro-o-xylene was used in solid-phase synthesis of large combinatorial variations of fundamental peptide unit.

Technology Process of 1,2-Bis(chloromethyl)benzene

There total 17 articles about 1,2-Bis(chloromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%