DL-THREITOL

Base Information

• Chemical Name: DL-THREITOL
• CAS No.: 6968-16-7
• Molecular Formula: C4H10 O4
• Molecular Weight: 122.121
• Mol file: 6968-16-7.mol

Synonyms:1,2,3,4-Butanetetrol,(R*,R*)-; Threitol (6CI,7CI,8CI); (?à)-Threitol; DL-Tetritol; DL-Threitol; NSC 20660; Threit

Chemical Property of DL-THREITOL

Chemical Property:

• Melting Point: 90°C
• Refractive Index: 1.4502 (estimate)
• Boiling Point: 147.51°C (rough estimate)
• PSA: 80.92000
• Density: 1.0151 (rough estimate)
• LogP: -2.30720
• Water Solubility.: 898g/L(25 oC)

Purity/Quality:

99% ^*data from raw suppliers

DL-Threitol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: DL-Threitol is a sugar molecule and is usedul in the synthesis of pharmaceuticals. A diastereomer of erythritol. Cryoprotectant.

Technology Process of DL-THREITOL

There total 55 articles about DL-THREITOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cis-2,3-epoxy-1,4-butanediol (4440-87-3,63621-92-1) → 1,2,3,4-butanetetrol (2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6)

Guidance literature:

With water; at 100 ℃; for 9h;

DOI:10.1021/jo702401t

Reference yield: 60.0%

1,4-butenediol (821-11-4,6117-80-2,110-64-5) → 1,2,3,4-butanetetrol (2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6)

Guidance literature:

With potassium permanganate; dihydrogen peroxide; In water; acetone; at 0 ℃; for 2h; Temperature; Inert atmosphere; Green chemistry;

DOI:10.1039/c5ra01646k

Reference yield: 53.6%

cellulose (9004-34-6) → 1,2,3,4-butanetetrol (2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6) + ethylene glycol (107-21-1)

Guidance literature:

With ruthenium-carbon composite; hydrogen; In water; at 215 ℃; for 1.5h; under 39003.9 Torr; Reagent/catalyst; Catalytic behavior; Autoclave;

DOI:10.1039/c6ra27524a

upstream raw materials:

(3-hydroxymethyl-oxiranyl)-methanol

3,4-butenediol

1,4-dibromo-2-butene

dimethyl tartrate

Downstream raw materials:

(+/-)-trans-tetrahydrofuran-3,4-diol

formic acid

meso-2,2'-diphenyl-tetrahydro-[4,4']bi[1,3,2]dioxaborolyl

2,2'-diethyl-tetrahydro-[4,4']bi[1,3,2]dioxaborolyl

Refernces

• 1、 Ban, Chunghyeon,Yang, Seungdo,Kim, Hyungjoo,Kim, Do Heui. "Effect of Cu addition to carbon-supported Ru catalysts on hydrogenation of alginic acid into sugar alcohols". . p. 98 - 104. Retrieved 2019/04/17.
• 2、 Chai, Jiachun,Zhu, Shanhui,Cen, Youliang,Guo, Jing,Wang, Jianguo,Fan, Weibin. "Effect of tungsten surface density of WO3-ZrO2 on its catalytic performance in hydrogenolysis of cellulose to ethylene glycol". . p. 8567 - 8574. Retrieved 2017/02/10.