Ethanone, 1-(2-ethenylphenyl)- (9CI)

Base Information

• Chemical Name: Ethanone, 1-(2-ethenylphenyl)- (9CI)
• CAS No.: 52095-40-6
• Molecular Formula: C10H10 O
• Molecular Weight: 146.189
• Hs Code.: 2914399090
• Mol file: 52095-40-6.mol

Synonyms:Acetophenone,2'-vinyl- (5CI); 1-(2-Vinylphenyl)ethanone; 2-Acetylstyrene; NSC 3438;o-Vinylacetophenone

Chemical Property of Ethanone, 1-(2-ethenylphenyl)- (9CI)

Chemical Property:

• Vapor Pressure: 0.0367mmHg at 25°C
• Boiling Point: 241°Cat760mmHg
• Flash Point: 95.4°C
• PSA: 17.07000
• Density: 0.995g/cm³
• LogP: 2.53220

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-(2-ethenylphenyl)- (9CI)

There total 19 articles about Ethanone, 1-(2-ethenylphenyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-bromophenyl methyl ketone (2142-69-0) + 2,4,6-trivinylcyclotriboroxane*pyridine complex → o-acetylstyrene (52095-40-6)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; water; for 14h; Heating;

DOI:10.1021/ol0506922

Reference yield: 90.0%

tri-n-butyl(vinyl)tin (7486-35-3) + trifluoromethanesulfonic acid 2-acetylphenyl ester (129849-05-4) → o-acetylstyrene (52095-40-6)

Guidance literature:

With lithium chloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane; In various solvent(s); for 2h; Ambient temperature;

DOI:10.1021/jo00310a014

Reference yield: 84.0%

vinylboronic acid (4363-34-2) + 2-bromophenyl methyl ketone (2142-69-0) → o-acetylstyrene (52095-40-6)

Guidance literature:

With cis,cis,cis-tetrakis[(diphenylphosphanyl)methyl]cyclopentane; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); In xylene; at 130 ℃; for 20h;

DOI:10.1002/ejoc.200300627

upstream raw materials:

tri-n-butyl(vinyl)tin

trifluoromethanesulfonic acid 2-acetylphenyl ester

1-(2-chlorophenyl)ethanone

dimethyl sulfate

Downstream raw materials:

methanesulfonic acid [1-(2-vinyl-phenyl)ethylidene]hydrazide

1-[4-[4[-5-(2-acetylphenyl)-4,5-dihydroisoxazol-3-yl]thiazol-2-yl]-1-piperidyl]-2-[3,5-bis(difluoromethyl)pyrazol-1-yl]ethanone

methanesulfonic acid [1-{2-[3-(2-chloro-acetyl)-4,5-dihydro-isoxazol-5-yl]phenyl}ethylidene]hydrazide

methanesulfonic acid [1-{2-[3-(2-{1-[2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)acetyl]piperidin-4-yl}thiazol-4-yl)-4,5-dihydro-isoxazol-5-yl]-phenyl}ethylidene]hydrazide

Refernces

• 1、 Shen, Guoli,Liu, Haojie,Chen, Jingchao,He, Zhenxiu,Zhou, Yongyun,Wang, Lin,Luo, Yang,Su, Zhimin,Fan, Baomin. "Zinc salt-catalyzed reduction of α-aryl imino esters, diketones and phenylacetylenes with water as hydrogen source". supporting information. p. 3601 - 3610. Retrieved 2021/05/04.
• 2、 Garcia-Rubin, Silvia,Gonzalez-Rodriguez, Carlos,Garcia-Yebra, Cristina,Varela, Jesus A.,Esteruelas, Miguel A.,Saa, Carlos. "Dihydrobiphenylenes through ruthenium-catalyzed [2+2+2] cycloadditions of ortho-alkenylarylacetylenes with alkynes". supporting information. p. 1841 - 1844. Retrieved 2014/03/21.