Aminoguanidine sulfate

Base Information

• Chemical Name: Aminoguanidine sulfate
• CAS No.: 996-19-0
• Molecular Formula: C2H14N8O4S
• Molecular Weight: 246.25
• Hs Code.: 29280000
• European Community (EC) Number: 213-945-0
• NSC Number: 7888
• UNII: 62X13LJ94Q
• DSSTox Substance ID: DTXSID401020920
• Wikidata: Q27263524
• ChEMBL ID: CHEMBL1256617
• Mol file: 996-19-0.mol

Synonyms:aminoguanidine;aminoguanidine sulfate;hydrazinecarboximidamide;monoaminoguanidine;pimagedine;pimagedine hydrochloride

Chemical Property of Aminoguanidine sulfate

Chemical Property:

• Appearance/Colour: White or colorless crystal
• Melting Point: 200 °C
• Boiling Point: 261.4 °C at 760 mmHg
• Flash Point: 111.9 °C
• PSA: 258.82000
• Density: 1.36 g/cm3 (20℃)
• LogP: 0.89680
• Storage Temp.: Store below +30°C.
• Solubility.: 170g/l
• Water Solubility.: almost transparency
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 172.02662592
• Heavy Atom Count: 10
• Complexity: 123

Purity/Quality:

98% ^*data from raw suppliers

Aminoguanidine hemisulfate salt ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(=NN)(N)N.OS(=O)(=O)O
• Uses: Aminoguanidine inhibits both constitutive and inducible nitric oxide synthetase. Aminoguanidine has also been used to study the effects of nitric oxide on ovulation and ovarian steroidogenesis and prostaglandin production.

Technology Process of Aminoguanidine sulfate

There total 2 articles about Aminoguanidine sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

aminoguanidine bicarbonate (2582-30-1) → aminoguanidine sulfate (996-19-0,1068-42-4)

Guidance literature:

With sulfuric acid; In water; at 80 ℃;

DOI:10.1080/10426500802479877

Reference yield:

hydrazinecarboximidamide hydrochloride (16139-18-7) → aminoguanidine sulfate (996-19-0,1068-42-4)

Guidance literature:

With silver sulfate; In water; at 20 ℃; for 2h;

DOI:10.1039/c6ra12109h

Reference yield: 92.0%

2,4,6-trinitrobenzaldehyde (606-34-8) + aminoguanidine sulfate (996-19-0,1068-42-4) → bis(N-(2,4,6-trinitrobenzylideneamino)guanidinium) sulphate

Guidance literature:

In ethanol; at 60 ℃; for 24h;

DOI:10.1039/c4nj01849d

upstream raw materials:

aminoguanidine bicarbonate

hydrazinecarboximidamide hydrochloride

Downstream raw materials:

1--3-isopropylidenamino-guanidin

1--3-isopropylidenamino-guanidin

1--3-isopropylidenamino-guanidin

1--3-diaethylmethylenamino-guanidin

Refernces

• 1、 Klapoetke, Thomas M.,Mayer, Peter,Stierstorfer, Joerg. "Crystal structures of mono-, Di-, and triaminoguanidinium sulfate, as well as azidoformamidinium sulfate: Important precursors for syntheses of nitrogen rich ionic vompounds". experimental part. p. 2393 - 2407. Retrieved 2010/03/25.