4-(Trifluoromethyl)thiazol-2-amine

Base Information Edit

Chemical Name:4-(Trifluoromethyl)thiazol-2-amine
CAS No.:349-49-5
Molecular Formula:C4H3F3N2S
Molecular Weight:168.142
Hs Code.:2934100090
European Community (EC) Number:671-488-6
DSSTox Substance ID:DTXSID80188451
Nikkaji Number:J417.145D
Wikidata:Q72442887
Mol file:349-49-5.mol

Synonyms:349-49-5;4-(trifluoromethyl)thiazol-2-amine;4-(trifluoromethyl)-1,3-thiazol-2-amine;4-Trifluoromethyl-thiazole-2ylamine;2-amino-4-trifluoromethyl-1,3-thiazole;2-Amino-4-trifluoromethylthiazole;2-amino-4-(trifluoromethyl)thiazole;2-Thiazolamine, 4-(trifluoromethyl)-;4-(Trifluoromethyl)-2-thiazolamine;2-Amino-4-(trifluoromethyl)-1,3-thiazole;4-trifluoromethylthiazole-2ylamine;4-trifluoromethyl-thiazol-2-ylamine;C4H3F3N2S;MFCD00832759;4-trifluoromethyl-thiazol-2ylamine;SCHEMBL245790;4-trifluoromethyl-2-aminothiazole;DTXSID80188451;4-trifluoromethylthiazol-2-ylamine;C4-H3-F3-N2-S;4-Trifluoromethyl-thiazole-2-ylamine;BBL104259;GEO-02881;STL558386;AKOS000123903;AC-4447;CS-W009047;FS-1246;SY003850;A6136;AM20090546;BB 0260033;FT-0632003;EN300-36834;4-trifluoromethyl-thiazol-2-ylamine, AldrichCPR;A822476;AB-601/30915004;J-019809;J-513943;Z330920398

Suppliers and Price of 4-(Trifluoromethyl)thiazol-2-amine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Trifluoromethyl)-2-thiazolamine
2.5g
$ 275.00

SynQuest Laboratories
2-Amino-4-(trifluoromethyl)-1,3-thiazole
250 mg
$ 21.00

Sigma-Aldrich
2-Amino-4-trifluoromethylthiazole hydrobromide Aldrich
1g
$ 168.00

Oakwood
4-Trifluoromethyl-thiazole-2ylamine
250mg
$ 16.00

Medical Isotopes, Inc.
4-(Trifluoromethyl)-2-thiazolamine
500 mg
$ 625.00

Matrix Scientific
2-Amino-4-trifluoromethyl-1,3-thiazole
500mg
$ 166.00

Frontier Specialty Chemicals
2-Amino-4-(trifluoromethyl)-1,3-thiazole 98%
1g
$ 75.00

Crysdot
4-(Trifluoromethyl)thiazol-2-amine 97%
5g
$ 165.00

Chemenu
4-(trifluoromethyl)thiazol-2-amine 98%
5g
$ 163.00

Chemenu
4-(trifluoromethyl)thiazol-2-amine 98%
10g
$ 290.00

Total 59 raw suppliers

Chemical Property of 4-(Trifluoromethyl)thiazol-2-amine Edit

Chemical Property:

Vapor Pressure:0.16mmHg at 25°C
Melting Point:60-62 °C
Refractive Index:1.503
Boiling Point:214 °C at 760 mmHg
PKA:1.90±0.10(Predicted)
Flash Point:83.2 °C
PSA：67.15000
Density:1.558 g/cm³
LogP:2.32530
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:167.99690376
Heavy Atom Count:10
Complexity:126

Purity/Quality:

99%min ^*data from raw suppliers

4-(Trifluoromethyl)-2-thiazolamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 20/21/22-36/37/38-43-36
Safety Statements: 26-36/37/39-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=C(S1)N)C(F)(F)F
Uses 4-(Trifluoromethyl)-2-thiazolamine can be used to prepare phenethylthiazolylthiourea analogs as HIV-1 reverse transcriptase inhibitors. 4-(Trifluoromethyl)-2-thiazolamine can also be used to synthesize 2-amino benzamide derivatives as allosteric glucokinase activators.

Technology Process of 4-(Trifluoromethyl)thiazol-2-amine

There total 8 articles about 4-(Trifluoromethyl)thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%