2-Phenylbenzyl bromide

Base Information

• Chemical Name: 2-Phenylbenzyl bromide
• CAS No.: 19853-09-9
• Molecular Formula: C13H11 Br
• Molecular Weight: 247.134
• Hs Code.: 2903999090
• European Community (EC) Number: 628-751-5
• NSC Number: 97772
• DSSTox Substance ID: DTXSID70294737
• Nikkaji Number: J1.355.904J
• Wikidata: Q82034187
• Mol file: 19853-09-9.mol

Synonyms:2-Phenylbenzyl bromide;19853-09-9;2-phenylbenzylbromide;1-(bromomethyl)-2-phenylbenzene;2-(Bromomethyl)biphenyl;1,1'-Biphenyl, 2-(bromomethyl)-;2-(bromomethyl)-1,1'-biphenyl;bromomethylbiphenyl;bromomethyl biphenyl;NSC97772;2-Bromomethylbiphenyl;o-phenylbenzyl bromide;(bromomethyl) biphenyl;2-phenyl benzyl bromide;2-phenyl-benzyl bromide;2-(Bromomethyl)-biphenyl;SCHEMBL471;biphenyl-2-ylmethyl bromide;1-bromomethyl-2-phenylbenzene;2-Bromomethyl-1,1'-biphenyl;2-Phenylbenzyl bromide, 97%;(2-Phenyl)-phenylmethyl bromide;DTXSID70294737;SEXZHJJUKFXNDY-UHFFFAOYSA-N;MFCD00075454;NSC-97772;AKOS015889176;CS-W003996;AS-44164;EN300-1870337

Chemical Property of 2-Phenylbenzyl bromide

Chemical Property:

• Vapor Pressure: 1.77E-05mmHg at 25°C
• Melting Point: 45-46 °C
• Refractive Index: n20/D 1.6280(lit.)
• Boiling Point: 374.7°Cat760mmHg
• Flash Point: 169°C
• PSA: 0.00000
• Density: 1.341g/cm³
• LogP: 4.24850
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 246.00441
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Phenylbenzyl bromide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-28-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC=C2CBr
• Uses: 2-Phenylbenzyl bromide may be used in the synthesis of a parent skeleton of 9H-fluorene.

Technology Process of 2-Phenylbenzyl bromide

There total 18 articles about 2-Phenylbenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.6%

2-biphenylmethanol (2928-43-0) → 2-phenylbenzyl bromide (19853-09-9)

Guidance literature:

With hydrogen bromide; for 21h; Heating;

DOI:10.1021/ja00034a011

Reference yield: 96.5%

2-methylbiphenyl (643-58-3) → 2-phenylbenzyl bromide (19853-09-9)

Guidance literature:

With tert.-butylhydroperoxide; N-Bromosuccinimide; In cyclohexane; at 50 ℃; for 4h; Reagent/catalyst; Temperature;

Reference yield: 86.0%

sodium metabisulfite + Na2 S2 O5 + 2-methylbiphenyl (643-58-3) → 2-phenylbenzyl bromide (19853-09-9)

Guidance literature:

With N-Bromosuccinimide; In nitrogen; water; chlorobenzene;

upstream raw materials:

2-biphenylmethanol

2-methylbiphenyl

biphenyl-2-carboxylic acid methyl ester

biphenyl-2-carbonitrile

Downstream raw materials:

4-(9-phenanthryl)phenol

2-([1,1'-biphenyl]-2-yl)-1-(4-methoxyphenyl)ethan-1-one

(2R,4R) diethyl-4-(tert-butyloxycarbonylamino)-1-(2-phenylbenzyl)pyrrolidine-2,4-dicarboxylate

1,2-bis(biphenyl-2-yl)ethane

Refernces

• 1、 Zhang, Lele,Cheng, Songbo,Hang,Defeng. "A facile synthesis of 3-(chloromethyl)-2-methyl-1,1'-biphenyl". . p. 3009 - 3011. Retrieved 2019.
• 2、 Houle, Camille,Savoie, Paul R.,Davies, Clotilde,Jardel, Damien,Champagne, Pier Alexandre,Bibal, Brigitte,Paquin, Jean-Fran?ois. "Thiourea-Catalyzed C?F Bond Activation: Amination of Benzylic Fluorides". supporting information. p. 10620 - 10625. Retrieved 2020/07/24.