2-Biphenylmethanol

Base Information

• Chemical Name: 2-Biphenylmethanol
• CAS No.: 2928-43-0
• Molecular Formula: C13H12O
• Molecular Weight: 184.238
• Hs Code.: 2906299090
• European Community (EC) Number: 220-892-7
• NSC Number: 97773
• DSSTox Substance ID: DTXSID801031183
• Nikkaji Number: J236.209K
• Wikidata: Q82886618
• ChEMBL ID: CHEMBL333825
• Mol file: 2928-43-0.mol

Synonyms:2-Biphenylmethanol;2928-43-0;[1,1'-Biphenyl]-2-ylmethanol;(2-phenylphenyl)methanol;Biphenylmethanol;[1,1'-Biphenyl]-2-methanol;Biphenyl-2-methanol;2-Phenylbenzyl alcohol;(1,1'-Biphenyl)methanol;[1,1-Biphenyl]-2-ylmethanol;o-Phenylbenzyl alcohol;Biphenyl-2-yl-methanol;41376-19-6;EINECS 220-892-7;(1,1'-Biphenyl)-2-methanol;biphenyl-2-ylmethanol;(2-phenylphenyl)methan-1-ol;NSC97773;MFCD00004620;2-phenylbenzylalcohol;2-hydroxymethylbiphenyl;o-Phenyl benzyl alcohol;Maybridge1_004234;ortho-phenylbenzyl alcohol;2-(Hydroxymethyl)biphenyl;2-Biphenylmethanol, 99%;1,1'-Biphenyl-2-methanol;SCHEMBL117091;CHEMBL333825;DAlc2-H_000049;HMS553I12;VKTQADPEPIVMHK-UHFFFAOYSA-;DTXSID801031183;{[1,1'-biphenyl]-2-yl}methanol;AMY38634;[1,1'-Biphenyl]-2-ylmethanol #;JFD 03959;NSC 97773;NSC-97773;AKOS015856399;CS-W017001;AS-58698;LS-44426;FT-0613327;EN300-1862841;A819865;J-017467

Chemical Property of 2-Biphenylmethanol

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 4.83E-05mmHg at 25°C
• Melting Point: 46-48 ºC
• Refractive Index: 1.595
• Boiling Point: 335.1 °C at 760 mmHg
• PKA: 14.25±0.10(Predicted)
• Flash Point: 162.3 °C
• PSA: 20.23000
• Density: 1.093 g/cm³
• LogP: 2.84590
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 184.088815002
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

99.0% ^*data from raw suppliers

2-Biphenylmethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC=C2CO
• Uses: 2-Biphenylmethanol was used in the synthesis of o-ethynylbiphenyl and o-alkynylstyrene derivatives.

Technology Process of 2-Biphenylmethanol

There total 41 articles about 2-Biphenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Biphenylcarboxylic acid (947-84-2) → 2-biphenylmethanol (2928-43-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 - 20 ℃; for 8.5h; Inert atmosphere; Schlenk technique;

DOI:10.1021/om5001869

Reference yield: 98.7%

biphenyl-2-carboxylic acid methyl ester (16605-99-5) → 2-biphenylmethanol (2928-43-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/ja00034a011

Reference yield: 98.0%

2-Phenylbenzaldehyde (1203-68-5) → 2-biphenylmethanol (2928-43-0)

Guidance literature:

With CdS(x)Se(1-x) x:0-1;; cesium acetate; para-thiocresol; In toluene; Sealed tube; Inert atmosphere; Irradiation;

DOI:10.1021/acs.joc.0c02627

upstream raw materials:

formaldehyd

biphenyl-2-ylmagnesium iodide

2-Phenylbenzaldehyde

2-phenylbenzylamine

Downstream raw materials:

2-fluorobiphenyl

2-Phenylbenzaldehyde

3-phenyl-benzyl alcohol

[biphenyl-2-ylmethyl-(2-nitro-benzenesulfonyl)-aminooxy]-acetic acid tert-butyl ester

Refernces

• 1、 Gholap, Sandeep Suryabhan,Dakhil, Abdullah Al,Chakraborty, Priyanka,Li, Huaifeng,Dutta, Indranil,Das, Pradip K.,Huang, Kuo-Wei. "Efficient and chemoselective hydrogenation of aldehydes catalyzed by well-defined PN3-pincer manganese(ii) catalyst precursors: An application in furfural conversion". supporting information. p. 11815 - 11818. Retrieved 2021/11/30.
• 2、 Hajipour, Abdol R.,Khorsandi, Zahra,Ahmadi, Mehnoosh,Jouypazadeh, Hamidreza,Mohammadi, Bahareh,Farrokhpour, Hossein. "Pd/Cu-Free Cobalt-Catalyzed Suzuki and Heck Using Green Bio-Magnetic Hybrid and DFT-Based Theoretical Study". . p. 2842 - 2850. Retrieved 2021/02/01.