Rosmanol

Base Information

• Chemical Name: Rosmanol
• CAS No.: 80225-53-2
• Molecular Formula: C20H26O5
• Molecular Weight: 346.423
• Hs Code.: 2932999099
• Mol file: 80225-53-2.mol

Synonyms:2H-10,4a-(Epoxymethano)phenanthren-12-one,1,3,4,9,10,10a-hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-,[4aR-(4aa,9b,10a,10ab)]-;Rosmanol;

Chemical Property of Rosmanol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 212-213 °C(Solv: ethyl ether (60-29-7))
• Refractive Index: 1.625
• Boiling Point: 574.186 °C at 760 mmHg
• PKA: 9.07±0.60(Predicted)
• Flash Point: 205.663 °C
• PSA: 86.99000
• Density: 1.33
• LogP: 3.25770
• Storage Temp.: 2-8°C

Purity/Quality:

≥98% ^*data from raw suppliers

Rosmarinic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Rosmanol

There total 2 articles about Rosmanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

carnosol (5957-80-2) → Oxydesaminoisorosmaricin (80225-53-2)

Guidance literature:

With sodium hydrogencarbonate; In acetone; at 20 ℃; for 6.5h;

DOI:10.1021/np010565o

Reference yield:

carnosol (5957-80-2) → epi-rosmanol (93380-12-2) + Oxydesaminoisorosmaricin (80225-53-2)

Guidance literature:

With sodium hydrogencarbonate; In acetone; at 20 ℃; for 1.5h;

DOI:10.1021/jf050685s

Reference yield: 21.0%

Oxydesaminoisorosmaricin (80225-53-2) → rosmanol quinone (121927-71-7) + galdosol (52591-18-1)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 2.5h;

DOI:10.1021/np010565o

upstream raw materials:

carnosol

Downstream raw materials:

rosmanol quinone

galdosol

Refernces

• 1、 Masuda, Toshiya,Kirikihira, Takuya,Takeda, Yoshio. "Recovery of antioxidant activity from carnosol quinone: Antioxidants obtained from a water-promoted conversion of carnosol quinone". . p. 6831 - 6834. Retrieved 2007/10/03.