Tert-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate

Base Information Edit

Chemical Name:Tert-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate
CAS No.:185099-67-6
Molecular Formula:C12H19NO3
Molecular Weight:225.288
Hs Code.:29399990
European Community (EC) Number:626-467-6
DSSTox Substance ID:DTXSID30383393
Nikkaji Number:J1.584.622D
Mol file:185099-67-6.mol

Synonyms:185099-67-6;tert-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate;N-Boc-nortropinone;N-Boc-4-Nortropinone;N-(tert-Butoxycarbonyl)nortropinone;8-Boc-8-azabicyclo[3.2.1]octan-3-one;t-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate;Arachidicanhydride;3-Oxo-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester;SCHEMBL413300;DTXSID30383393;MENILFUADYEXNU-UHFFFAOYSA-N;AKOS004910704;AC-4223;CS-W001484;PB27511;PS-3552;SY004645;8-Boc-3-oxo-8-aza-bicyclo[3.2.1]octane;AM20090080;B3401;BB 0305191;FT-0600825;EN300-52945;A812919;W-206330;F0001-0668;Z763781734;N-(tert-Butoxycarbonyl)-8-azabicyclo[3.2.1]octan-3-one;tert-butyl 3-oxo-8-aza-bicyclo[3.2.1]octan-8-carboxylate;tert-Butyl 3-oxo-8-azabicyclo[3.2.1]octan-8-carboxylate;tert-Butyl 3-oxo-8-azaicyclo[3.2.1]octane-8-carboxylate;tert-butyl 3-oxo-8-aza-bicyclo[3.2.1]octane-8-carboxylate;3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester;3-oxo-8-aza-bicyclo[3.2.1]-octane-8-carboxylic acid tert-butyl ester;3-Oxo-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid, tert-butyl ester

Suppliers and Price of Tert-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Boc-nortropinone
2g
$ 322.00

TRC
N-Boc-nortropinone
50g
$ 490.00

TCI Chemical
N-(tert-Butoxycarbonyl)nortropinone >98.0%(HPLC)(N)
1g
$ 39.00

TCI Chemical
N-(tert-Butoxycarbonyl)nortropinone >98.0%(HPLC)(N)
5g
$ 115.00

SynQuest Laboratories
8-Azabicyclo[3.2.1]octan-3-one, N-Boc protected 97%
100 g
$ 250.00

Sigma-Aldrich
N-Boc-nortropinone ≥98.0% (HPLC)
5g
$ 242.00

Sigma-Aldrich
N-Boc-nortropinone ≥98.0% (HPLC)
1g
$ 65.20

Medical Isotopes, Inc.
N-Boc-nortropinone
1 g
$ 875.00

Matrix Scientific
tert-Butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate 95%
5g
$ 19.00

Matrix Scientific
tert-Butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate 95%
25g
$ 58.00

Total 110 raw suppliers

Chemical Property of Tert-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate Edit

Chemical Property:

Appearance/Colour:off-white solid
Vapor Pressure:0.000225mmHg at 25°C
Melting Point:70-74 °C
Refractive Index:1.507
Boiling Point:325.8 °C at 760 mmHg
PKA:-1.65±0.20(Predicted)
Flash Point:150.8 °C
PSA：46.61000
Density:1.139 g/cm³
LogP:2.05530
Storage Temp.:Store at 0-5°C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:225.13649347
Heavy Atom Count:16
Complexity:303

Purity/Quality:

99% ^*data from raw suppliers

N-Boc-nortropinone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41-36/37/38
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C2CCC1CC(=O)C2
Uses N-Boc-Nortropinone is a 8-azabicyclo[3.2.1]octane derivative useful as opioid receptor modulator. A 8-azabicyclo[3.2.1]octane derivative useful as opioid receptor modulator.

Technology Process of Tert-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate

There total 27 articles about Tert-butyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%