20(R)-Ginsenoside Rg2

Base Information

• Chemical Name: 20(R)-Ginsenoside Rg2
• CAS No.: 80952-72-3
• Molecular Formula: C₄₂H₇₂O₁₃
• Molecular Weight: 785.026
• Mol file: 80952-72-3.mol

Synonyms:(S)Ginsenoside Rg2;20(R)-Ginsenoside Rg2;Ginsenoside-Rg2;20(R)Ginsenoside Rg2;

Chemical Property of 20(R)-Ginsenoside Rg2

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 221-223°C
• Boiling Point: 881°C at 760 mmHg
• PKA: 12.85±0.70(Predicted)
• Flash Point: 486.6°C
• PSA: 218.99000
• Density: 1.3g/cm³
• LogP: 2.14740
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

20(R)-GinsenosideRg2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 20(R)-Ginsenoside Rg2 possesses potent bioactivities and abundance in natural sources such as the roots, rhizomes and stem-leaves of Panaz ginseng. Also, it exhibits stereoselective inhibitory effects of varying degrees on the ten UGT isoenzymes.

Technology Process of 20(R)-Ginsenoside Rg2

There total 4 articles about 20(R)-Ginsenoside Rg2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ginsenoside Re (52286-59-6) → 20(S)-ginsenoside Rg2 (52286-74-5,80952-72-3)

Guidance literature:

With β-glucosidase; at 85 ℃; for 1h; pH=5.5; Enzymatic reaction;

DOI:10.1007/s10600-017-2025-0

Reference yield:

ginsenoside Re (52286-59-6) → ginsenoside F4 + 3β,12β,20,25-tetrahydroxy-dammarane (80952-74-5) + 3β,12β,20,25-tetrahydroxy-dammarane (80952-74-5) + ginsenoside 25-OH-Rg6 + ginsenoside 25-OH-F4 + 20(S)-ginsenoside Rg2 (52286-74-5,80952-72-3) + 6α-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl]-5R,9R,13R-dammarane-20(21),24(25)-diene-3β,12β-diol + 3β,12β,20-trihydroxy-dammar-24-ene

Guidance literature:

With dodecatungstophosphoric acid hexahydrate; water; at 80 ℃;

DOI:10.1039/c6nj01702a

Reference yield:

→ Ginsenosid Rg(2) (52286-74-5,80952-72-3)

Guidance literature:

Ginsenosid Re (II): part. Hydrolyse;

DOI:10.1248/cpb.22.2407

upstream raw materials:

ginsenoside Re

Refernces

• 1、 Xiu, Yang,Zhao, Huanxi,Gao, Yue,Liu, Wenlong,Liu, Shuying. "Chemical transformation of ginsenoside Re by a heteropoly acid investigated using HPLC-MS: N/HRMS". . p. 9073 - 9080. Retrieved 2016/11/09.
• 2、 Sanada,Kondo,Shoji,et al.. "Studies on the saponins of Ginseng. II. Structures of ginsenoside Re, -Rf and -Rg2". . p. 2407 - 2412. Retrieved 2007/10/07.