p-Ethylacetophenone oxime

Base Information

• Chemical Name: p-Ethylacetophenone oxime
• CAS No.: 2089-32-9
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• NSC Number: 59493
• Nikkaji Number: J3.405.379K
• Mol file: 2089-32-9.mol

Synonyms:p-Ethylacetophenone oxime;4'-Ethylacetophenone oxime;1-(4-Ethylphenyl)ethanone oxime;Acetophenone, 4'-ethyl-, oxime;Ethanone, 1-(4-ethylphenyl)-, oxime;BRN 2248141;2089-32-9;(NZ)-N-[1-(4-ethylphenyl)ethylidene]hydroxylamine;SCHEMBL19938067;NSC59493;NSC 59493;NSC-59493;4-07-00-00726 (Beilstein Handbook Reference)

Chemical Property of p-Ethylacetophenone oxime

Chemical Property:

• Vapor Pressure: 0.00289mmHg at 25°C
• Boiling Point: 272.9°C at 760 mmHg
• Flash Point: 159.4°C
• Density: 0.98g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 163.099714038
• Heavy Atom Count: 12
• Complexity: 157

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC=C(C=C1)C(=NO)C
• Isomeric SMILES: CCC1=CC=C(C=C1)/C(=N\O)/C

Technology Process of p-Ethylacetophenone oxime

There total 2 articles about p-Ethylacetophenone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-ethylacetophenone (937-30-4) → 1-(p-ethylphenyl)ethanone oxime (2089-32-9)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; water; at 95 ℃;

DOI:10.1021/acs.orglett.6b03155

Reference yield:

→ 1-(p-ethylphenyl)ethanone oxime (2089-32-9)

Guidance literature:

With ethanol; hydroxylamine hydrochloride; sodium carbonate;

Reference yield: 95.0%

1-(p-ethylphenyl)ethanone oxime (2089-32-9) → N-(4-ethylphenyl)acetamide (3663-34-1)

Guidance literature:

With 10-methyl-9-phenylacridin-10-ium perchlorate; In 1,2-dichloro-ethane; at 20 ℃; for 5h; Irradiation; Sealed tube;

DOI:10.1021/acs.orglett.0c02168

upstream raw materials:

4-ethylacetophenone

Downstream raw materials:

1-Vinyl-2-(p-ethylphenyl)pyrrole

2-(p-Ethylphenyl)pyrrole

1-(4-Ethyl-phenyl)-ethanone O-{2-[1-(4-ethyl-phenyl)-eth-(E)-ylideneaminooxy]-ethyl}-oxime

C₂₃H₂₉NO₃

Refernces

• 1、 Liang, Jingwen,Rao, Yingqi,Zhu, Weidong,Wen, Tingting,Huang, Junjie,Chen, Zhichao,Chen, Lu,Li, Yibiao,Chen, Xiuwen,Zhu, Zhongzhi. "AgNO3as Nitrogen Source for Cu-Catalyzed Cyclization of Oximes with Isocyanates: A Facile Route to N-2-Aryl-1,2,3-triazoles". supporting information. p. 7028 - 7032. Retrieved 2021/09/14.
• 2、 Zhou, Peiqi,Huang, Yubing,Wu, Wanqing,Yu, Wentao,Li, Jianxiao,Zhu, Zhongzhi,Jiang, Huanfeng. "Direct access to bis-S-heterocycles via copper-catalyzed three component tandem cyclization using S8 as a sulfur source". . p. 3424 - 3432. Retrieved 2019/04/01.